All bikes are a compromise. Increasing wheel size by 10% just brings a different set of compromises, but it’s no more significant than changing chainstay length, bottom bracket drop or head angle, all of which also tend to change with the larger wheel. If you compare a 26″ bike and a 29er there will be a lot more that is different than just the wheel size and it’s debatable whether the wheel size would even be the most significant difference.
So, the trick is just to pick the bike that’s best suited to the type of riding that you do, regardless of wheel size. Unfortunately that’s a lot harder than it sounds. I ride on trails that vary from smooth to really rather rough and go from pointing up at silly angles to pointing down at even more silly angles. I want a bike that rolls over bumps nicely, where the front wheel stays firmly planted on the trail no matter how steep the climb, but which can be lofted up with the greatest of ease when I want to. It needs to be comfortable but efficient, stable but playful etc. The problem is that such a bike doesn’t exist and whatever I pick is going to be better than the alternatives on some bits of trail and worse on others. In fact it’s almost impossible to decide what is best overall, particularly when you factor in variations due to weather, your fitness etc.
So, you have two choices: either just pick a bike you like the look of and ride the damn thing, or spend endless hours in pointless online discussions about what is best and what might ultimately prove more popular 🙂