nxgater, the vast majority of men and women overlap each other in basic proportions. The primary differences are at the extreme ends in overall height. The frame itself is unimportant because you can add/remove stack with spacers and stem angles. You can add/remove reach with different length stems or even bars. Even shoulder widths and hand sizes are generally consistent for men and women of equal height. The main difference as one person mentioned above, is in the distance between the ischial tuberosities and what’s exposed around the perineum. Still, there is mostly overlap there as well. The key is to make bikes for people, whether they have bad flexibility or can bend in half. Whether they’re 4’10” or 6’6″ If you’ve ever seen a size 44cm or 64cm road bike, you’ll know that many compromises to frame geometry have been made to accommodate 700c wheels. Why aren’t 44cm bikes built around 650b wheels. Why aren’t 64cm bikes built around 36″ wheels?