Once you’ve got reliable spaceflight, you can just fire your wastes into the sun anyway. Vitrify it on earth and lift it up in your space elevator.
I think we should be going… They should be viewed as stepping stones, getting back to the moon isn’t an achievement in itself but it gives us better access to orbit (smaller gravity well- build factory on moon, build stuff on moon, launch into earth orbit) Zero gee and low gee have lots of manufacturing potential, not to mention the access to raw materials. Earth orbit is probably going to be more important than the moon itself in the long run though. And there’s all sorts of socio-politico-technical reasons why it would be good.
Also, spaceships are awesome.