The Titus Roadrunner from PX looks really good and has a lifetime frame warranty, the tyre clearance you want and the ability to run proper mudguards.
It was on special recently at around £1700 with SRAM Force 1x. If the stack was higher I’d have bought one and rebuilt it 2x, selling most (nearly all actually) of the new bits attached to the titanium frame. Some swapping around of bits and a little eBay action would have yielded a really good value Ti all-season rough roadie.
Road disc is silly for a fair weather only bike IMHO, but yeah for winter/all seasons use it’s worth the extra weight, complexity, spoke offset issues…
I currently ride an Equilibrium Disc on old MTB 29er QR disc wheels with 28mm tyres and proper mudguards and it’s pretty great actually. It’s heavy but rides sweetly. It fits me better than a Roadrunner would, otherwise I’d definitely have gone for one.
My summer bike is a Domane SLR rim brake and it’s superb. Older Roubaix’s are excellent too, SL3/SL4 era, they ride better than the newer ones IME and bikes don’t actually get significantly better than that. But if you do a lot of dirty wet weather riding it’s worth getting discs, and Ti will brush off shitty conditions better than any other material.