Did this last May over 6 days. I’m not particularly skilled or fit – 35 miles was our longest day. A few observations:
On day 1 don’t be seduced by the pictures of Colwyd Reservoir – most of the track alongside and the climb at the end aren’t rideable and it’s a hell of a climb to get to it – enjoy the Marin trail instead.
Strata Florida is a swamp fest. It was relatively dry when we did it and the water was still shin deep. Take the fire road alternative.
Take care with route finding – there are places where you could lose hours over a wrong turn.
The weather will make or break it. There are some exposed sections and while for the most part the trails are good, the Black Mountain section is very indistinct once you’ve reached the summit.
Much of the climbing is on fire roads so rideable but it wears you down. This is especially so on the last day.
Some more info https://singletrackworld.com/forum/topic/welsh-coast-to-coast-1/