I have an 29er Inbred slot dropout SS.
My experience was that a Shimano QR wouldn’t stay put, even a bolted skewer moved on steep hills. The fix for me was a surly chain tug (Drive side only), it has two holes in the tug so you can switch around depending if it’s at the front or back of the slot. It wasn’t cheap, and I had to clean most of the patch-lock of the bolt so I could turn it by hand, but is a quality bit of kit that fits the Inbred well.
The other advice to avoid losing the chain is to use the right chain for the rings you have, go all 3/32″ or all 1/8″. I started with a mix (bitsa bike), and had problems, going to all 1/8″ has been great, silent and smooth no matter what.
Just need to upgrade the horid Juicy 3’s to Deores and I’ll be a happy chappy!
Edit to add also running 32×18