I’ve run fully run outers for many years now and certainly can say it’s a lot less hassle than partial runs. Rarely change gear cable now unless it snaps, and the outer only gets changed when the ends start fraying, but good quality ferules seem to help. I can’t remember where I got them, but they’re a harder sort of ferule and seem to resist splitting at the shifter end, so the outer doesn’t fray so easily.
I don’t use any special sealed ends, just the ferules, but definitely SP41 is the stuff you want for outers. Pair with any old stainless steel cable.