Send and wait will get you precisely nowhere. Usually on Total Jobs there will be an agency name and contact details. Send your CV and cover letter, give it five minutes and phone 'em. You want to give the impression that you want the job and I mean really want it.
I was out for 6 months and sent a LOT of CV's. For the first 3-4 months I as using the "press and pray" approach and not getting anywhere. Started ringing the agencies straight away and it made a difference.
The other thing to consider that stuff sent through Total Jobs can sometimes go astray. At least if you contact the agency direct and they've not got your stuff you can send it straight to them.
Good Luck!