Tindall captain…will resume his midfield partnership with Shontayne Hape.
Toby Flood is to return at fly-half, while Saracens scrum-half Richard Wigglesworth comes in for Danny Care.
Ben Foden and Chris Ashton will be handed their first starts of the summer, with Mark Cueto retaining his place on the left wing.
In the pack, Easter, Tom Wood and Hendrie Fourie will form a new-look back row, while Alex Corbisiero, Steve Thompson and Dan Cole are to be named as the front row.
Courtney Lawes has recovered from the neck injury he sustained during a trial match last month to return to the second row, where he will partner Louis Deacon.
It is understood that there will be no place in the match 22 for Gloucester wing Charlie Sharples or Harlequins wing Ugo Monye.
The headline change to the Wales side will see Gavin Henson return at inside centre, with Jamie Roberts switching to 13.
James Hook, fit again after a shoulder injury, will start at full-back while Rhys Priestland continues at fly-half, having deputised impressively for Stephen Jones, who was forced to withdraw moments before kick-off last Saturday with a calf injury.
Lions prop Adam Jones returns at tighthead prop while Luke Charteris comes into the second row in place of Bradley Davies.
GAVIN Henson is poised to start for Wales against England on Saturday — with James Hook expected to line up at full-back.
And Lloyd Burns and Luke Charteris are expected to feature in a pack that looks likely to contain four Dragons.
Warren Gatland was set to announce the changes when he named his team at lunchtime today.
For Henson, it is all or nothing time, the gilt-edged chance he has been waiting for to book his World Cup ticket.
He sat out the 23-19 defeat against Martin Johnson’s side at Twickenham when Jamie Roberts, Jonathan Davies and Scott Williams all sought to advance their claims.
But, according to a well-placed source, Henson has apparently looked “a class apart” in training.
Gatland is unlikely to take all four centres but in Henson’s favour is his ability to operate as a playmaker, allied to vast experience that has seen him feature in two Grand Slams.
But he still has to impress Gatland in a game situation and that is why the match in Cardiff this weekend will be of huge importance.
It will also be a big game for Hook. The gifted Perpignan-bound utility back would doubtless have preferred to feature at fly-half but Priestland has made a major impression in the pivotal role and is pushing hard to be considered first choice for the World Cup opener against South Africa, with Stephen Jones continuing to be sidelined by the calf problem he sustained during the warm-up for last Saturday’s game.
With Jamie Roberts and Jonathan Davies making the running at centre, and Henson back in the frame, Hook finds himself being considered for the No. 15 role, where Gatland also has Lions Test man Lee Byrne at his disposal.
Former Cross Keys hooker Burns is due to come in for his first start, after Huw Bennett set the bar high at hooker last weekend, while Charteris is in line to feature in a pack that is tipped to include fellow Dragon Dan Lydiate and Sam Warburton.
Wales (possible): J. Hook; G. North, J. Roberts, G. Henson, S. Williams; R. Priestland, M. Phillips; P. James, L. Burns, C. Mitchell, L. Charteris, A. W. Jones, D. Lydiate, T. Faletau, S. Warburton (capt).
If that front five is true it could get very messy for Wales, although the first article from the telegraph suggests Adam Jones back at 3 which would be a positive. It looks increasingly likely that Byrne and Rees (maybe Hibbard as well) are crocked and wont be going Lloyd Burns is not ready. Suggest to me that Faletau must be likely to go ahead of Powell, someone should tell the selectors there are not motorways for him to escape down in golf buggies in NZ.
