Trp spyre are the best mechanical road disc I’ve ridden but like all mechanical discs will require some adjustment as pads wear, can be tinkly from rotor/pad contact, and cables prone to corrosion over a wet winter.
If you have budget for shimano hydros they are worth the extra money, no doubt; self adjusting as pads wear, great modulation, minimal maintenance, pistons have long throw so little if any rotor/pad contact when sprinting or climbing.
I’ve been very impressed with my shimano hydros and the sti shape is fantastic on the rs 685, only negative is lever rattle on rough roads but easily cured with a sliver of bar tape up in the hood top.