The tour de france may not be run off at 100% every day, and some days some riders have easy rides, but overall for a contender it is harder than some here have made it sound. The first week is usually run off super fast, then the contenders and climbers have to work hard in the mountains. In between there are often a few slower transition stages, but these still entail 25 mph averages at least over 100+ miles. Yes there are two rest days, but they still go out for a couple of hours. Crashes, injury and illness make things harder of course.
I am not saying it is harder than say rugby or boxing, but it is very tough.