What the Beard said about the bearing adjustment, it really is a 2 minute job, nowhere near the faff of cup&cone and if you keep on top of it they run very smoothly indeed.
I hate wheels that flex under heavy cornering or rub the brakes when climbing and the Ksyriums seem very good at not doing this so for me they’re ideal climbing wheels.
Comfort-wise I haven’t noticed any real difference compared to my ‘winter’ wheels (32-spoke handbuilts)
If you’re a 65KG Quintana lookalike the stiffness may be a bit much, otherwise just enjoy the improved cornering and acceleration, you’ll also appreciate the Exalith when you come to ride down the other side.
Like I said, you can probably buy better pure ‘climbing’ wheels for the SLR’s money but they’ll be compromised elsewhere, especially if you’re a bigger rider.