spent a fair while on these as i work in areas at high risk of P. falciparum and malarone gives me least trouble.
they can all have issues it depends on you your self. the damage malarone does to the livers less risky.
“Malaria is spread by the bite of an infected mosquito, which passes the malaria parasite (Plasmodium falciparum) into the bloodstream. Malarone prevents malaria by killing this parasite. For people who are already infected with malaria, Malarone also kills these parasites.
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http://www.antimalariatablets.co.uk/malaria-tablets/malarone/
Only folk i know who have got malaria are the folks in country live in and havnt been taking anti malarials OR are locals. Same live in people who say its due to the liver damage but happily pickle their liver in alcohol every night.
I have to use doxy instead of peniclilin based drugs so dont fancy risking building an immunity to it.