My Dad’s spent the last 25 years going through pretty much everything available in an attempt to improve his condition (fibromyalgia, CFS, injuries not healing)
One variable at a time, scientific method medical/biochemistry papers scoured, down the rabbit hole of ever-increasing, baffling complexity.
The key for him was finding out through trial an error what he was short of that was holding up, at various points, the processing of toxins in his body. Toxins (which can just be from exercise), if they can’t be dealt with, can be locked away by the body in fatty tissue and mineral deposits in connective tissues. The other key was vaso-dilators, as the mineral deposits tend to be in places with poor blood supply.
He’s currently on chelated zinc and magnesium, B6 and B12, and some fancy immune response-modifying collagen supplements, probably a few other things too.
Massively slow process, pain always accompanies increased repair, might be a few months between trying something new and finding out if the increased pain is good, or if he’s ballsed up.
Bizarre but true, decades-old injuries have been healing in reverse order, he’s only got a few left to go. Then he’s going to be aging in the standard direction again!