Antibiotic resistant bacteria

The same reason that some women use a plastering trowel to put make-up on, turning their faces into corpse-like masks.

Ah yes, but I am reliably informed that UV from sunbeds is extremely effective at dealing with skin colonisation by resistant strains, which is why Essex folk will have the last laugh on you grimy northerners.

Nah, UV resistance is common in bacteria too (and Archea and Fungi for that matter) 🙂
In fact, radiation resistance, chemical resistance, any kind of resistance you can think of, all occur naturally. If they start conjugating with antibiotic-resistant pathogens we might have a problem…

UV resistance is common in bacteria too (and Archea and Fungi for that matter)

Not at Essex levels. It’s like sitting inside the core at Bradwell Power Station.

On a serious note, the answer is that many fragrance molecules are fatiguing to the nose so after a while your sense of smell becomes dull, which is called temporary anosmia. The worst mistake you can make is to go and reapply the fragrance during the evening because you interfere with the evolution of topnote-middle-backnote and you overwhelm your fellow diners.

Some people are even anosmic to certain molecules in the same way that some people are colour-blind.

In addition, they have to get to the nose, so there are only so many molecular receptor shapes available.

I recommend you read The Emperor of Scent by Chandler Burr. It’s about the maverick perfumer Luca Turin who believes we actually perceive odour molecules not by their shape but by their atomic vibration. In another later book Turin proves his theory, claiming that he knows how to make a non-discolouring vanilla molecule (the holy grail of the industry) but so far nobody has been sufficiently convinced to want to build a pilot plant and make the molecule.

I’d heard about the atomic vibration theory, and don’t disbelieve. I’m not convinced about the cost of a pilot plant putting people off a new vanillin synthesis, because the potential upside is so huge.

a non-discolouring vanilla molecule (the holy grail of the industry)

😆