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The Coronavirus Discussion Thread.

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Well, the lettuce beat him. He’s gone.

Until next time, friend.


 
Posted : 23/03/2023 12:28 pm
Poopscoop reacted
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Aww i was waiting on his latest unfounded response. Has gotten me through a dull morning


 
Posted : 23/03/2023 12:30 pm
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Starts off almost reasonable but with a reference from a very untrustworthy source

Consistently fails to provide evidence for claims but links either to irrelevant material or material that doesn't say what they claim it does

Becomes increasingly unhinged and starts with the shadowy hidden forces manipulating governments for unexplained reasons

Throws abuse at other posters who have been nothing but polite (if a bit exasperated)

I think what comes next is the explicit pornography, isn't it? That's how it's gone every time before.

<edit> Oh, gone before the porn. Progress, of a sort. </edit>


 
Posted : 23/03/2023 12:31 pm
kelvin reacted
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He shall return. At a moment of national crisis, when the population needs a defender, a hero if you will... He shall return.


 
Posted : 23/03/2023 12:31 pm
dissonance, tjagain, Murray and 2 people reacted
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onewheelgood
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Starts off almost reasonable but with a reference from a very untrustworthy source

Consistently fails to provide evidence for claims but links either to irrelevant material or material that doesn’t say what they claim it does

I do think it's the same person that seems to do this every month or two. The MO is always the same, as you say- Almost reasonable at first then descends into a whole world of paranoia. Its probably a regular poster but creates these alter egos to try and prove "something"? Pertussis he really thinks he is trying to help us? I don't know.

Being totally serious here for a moment, I wonder if the posts are some release valve for something deeper going on on his head?

Perhaps I shouldn't have taken the pee so much. I'll think on that. It's just that it's so bloody exhausting to read the same stuff over and over.


 
Posted : 23/03/2023 12:41 pm
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Pertussis he really thinks he is trying to help us? I don’t know.

I know that is a typo, but it is properly relevant when talking about vaccines


 
Posted : 23/03/2023 12:48 pm
Poopscoop reacted
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^^ Ha, what an odd/ relevant typo for my mobile to come up with, as you say.


 
Posted : 23/03/2023 12:53 pm
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bloody left wing echo chamber.... i was having fun


 
Posted : 23/03/2023 12:59 pm
matt_outandabout, tjagain, onewheelgood and 1 people reacted
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I had adverse effects from my vaccination. I had a sore arm and spiked a temperature for a few hours

I was hoping for something similar to a euphoric coke hit.

I was disappointed 🙁


 
Posted : 23/03/2023 1:03 pm
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Oh, gone before the porn. Progress, of a sort.

Not sure about that. Surely the porn would have been a reward for putting up with the rubbish.
I was hoping to ask about how the list of pharma fines supported his argument about them being unaccountable.

Getting back on track I also got covid a couple of weeks back. Think for the same time unless previously it was symptom free.
No loss of taste or anything just went paddling on Saturday morning and whilst not feeling in the mood nothing obvious wrong. Midafternoon serious muscle pain and then headaches. Had a week of feeling tired and on/off headaches.
Be interesting to see how the spin class goes tonight since first proper pressure.


 
Posted : 23/03/2023 1:04 pm
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Be interesting to see how the spin class goes tonight since first proper pressure.

Go easy. My Max heart rate has not recovered from Covid before Christmas.


 
Posted : 23/03/2023 1:13 pm
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or the global Jewish conspiracy?

I await with baited breath every morning for the letter that informs me that it's either mine of my wife's turn to run either one or more of:

The print media, films and TV any number of major corporations, and/or governments. It must've been lost in the post.

The thing I will say is that for a shadowy all powerful body, we have terrible PR; we must get around to changing that at some point (when we're not busy running the place, obvs)


 
Posted : 23/03/2023 1:30 pm
tjagain, kelvin, theotherjonv and 1 people reacted
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On a proper Covid note:

mrs_oab contracted Covid a fortnight ago, having already been suffering from another virus and a chest infection to deal with.

The anti-virals kicked Covid nearly into touch, however the earlier virus has come back to bite - and it is shingles. It may be that covid is also present - she had a faint line again yesterday...

Bugger.


 
Posted : 23/03/2023 1:37 pm
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Lolz @: nickc.

The thing I will say is that for a shadowy all powerful body, we have terrible PR

thats a real gem ( not sarcastic!)


 
Posted : 23/03/2023 1:45 pm
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@matt_outandabout

Sorry to hear that mate.

I'm really sorry if I'm wrong (I have a terrible memory) but is it your wife that is immunosuppressed?

I got a text saying I could get anti viral drugs asap if I test positive, yet my old mum at 94 doesn't seem to qualify, oddly.


 
Posted : 23/03/2023 1:55 pm
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How do you know they've gone? Another thread?


 
Posted : 23/03/2023 1:55 pm
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...
Sorry to hear that, Matt.


 
Posted : 23/03/2023 1:56 pm
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Cougar
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How do you know they’ve gone? Another thread?

When I looked at their profile, their posting history had disappeared so I assumed that was due to bannage?


 
Posted : 23/03/2023 1:56 pm
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How do you know they’ve gone? Another thread?

Him being directly abusive towards Mark on the Boris Johnson thread...(now deleted). It's almost like he wanted to be banned at that point, to put him out of his misery.


 
Posted : 23/03/2023 1:58 pm
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^^ Oh, I didn't even see that.


 
Posted : 23/03/2023 2:02 pm
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is it your wife that is immunosuppressed?

Yep, that is why it is all rattling around... News to me that shingles is much more common in primary immune disorder patients - and no-one seems to know why.


 
Posted : 23/03/2023 2:05 pm
kelvin reacted
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Shingles is a function of immune deficiency anyhow - a latent form of a virus she's had since childhood which re-emerges if the conditions are right.

So I guess it's not surprising that whatever interaction her immune system has had with Covid has left her more vulnerable to it. It's why I only had mild Covid before Christmas, but came down with a nasty bacterial chest infection a couple of weeks later.

Horrible though, and she has my sympathy. Has she got decent pain control from the GP?


 
Posted : 23/03/2023 2:11 pm
kelvin reacted
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The worry is just never ending is it?

I hope things improve asap for her mate.


 
Posted : 23/03/2023 2:12 pm
kelvin reacted
 Del
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Damnit! I read the last 4 pages and no happy ending! 🤣

AXS of evil. Makes you think

At the very heart of the Big Derailleur Cabal, you mark my words.


 
Posted : 23/03/2023 3:02 pm
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Sorry to hear that Matt,I had the same thing happen back in 2020 after a dose of the original Covid.
As martin suggests,I think covid gave my immune system a kicking,which then let Shingles in(9 weeks).
Hope the pain is not too bad for her,I wouldn't wish it on anyone.


 
Posted : 23/03/2023 3:22 pm
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Cheers all - I don't think the pain control is great, they gave her an anti-depressant(?) but did not clock that she was already on a mild anti-depressant - she has stopped taking it. Currently taking ibuprofen and paracetamol.


 
Posted : 23/03/2023 3:39 pm
Poopscoop reacted
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Amitriptyline  ( I think) is often used for pain control in shingles IIRC.  Something todo withthe way it interacts with the nerve pathways?

For adults with mild pain, offer a trial of paracetamol alone or in combination with codeine or a nonsteroidal anti-inflammatory drug (NSAID), such as ibuprofen.

If this is not effective, or the person presents with severe pain, consider offering amitriptyline (off-label use), duloxetine (off-label use), gabapentin, or pregabalin.


 
Posted : 23/03/2023 4:01 pm
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If she's still suffering badly, she may be able to get something punchier. Co-codamol over the counter might be a good interim measure. Try a decent antihistamine as well, if it's an impossible itch.


 
Posted : 23/03/2023 4:04 pm
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Amitriptyline ( I think) is often used for pain control in shingles IIRC. Something todo withthe way it interacts with the nerve pathways?

If the pain results in poor sleep, it can prompt prescription of this as well… especially if getting up in the night due to bladder stuff. A complicated mix of off-label benefits that GPs need to consider beyond use as an anti-depressant.

[ I am not a doctor ]


 
Posted : 23/03/2023 4:06 pm
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Wow!, 5 pages of new posts so I ventured back to see what new information had triggered such a slew of responses only to find an ignorant troll, for gods sake just ignore the ****ing idiots as otherwise an informative thread gets polluted by a wave of shite.


 
Posted : 23/03/2023 4:09 pm
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I quite enjoy the entertainment value of conspiracy theories, and it's not as if they are difficult to counter.

Plus to be fair the thread had been inactive for several weeks so it's not as if it was a distraction from an ongoing serious debate. In all likelihood it will go back into hibernation for quite a while.

Matt - good to hear that your wife has made progress with covid and I hope she quickly makes the same with regards to shingles.

I know that whilst shingles is almost always not very serious, just very unpleasant and painful, it can on very rare occasions be really serious causing among other things nerve/brain/sight damage, so should never dismissed lightly.

I'm assuming she didn't have a shingles vaccine? Would that be appropriate for the future?


 
Posted : 23/03/2023 4:50 pm
Poopscoop reacted
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Plus to be fair the thread had been inactive for several weeks so it’s not as if it was a distraction from an ongoing serious debate. In all likelihood it will go back into hibernation for quite a while.

i'd like to get a plot of posting frequency on this thread overlaid with case rates. I think there would be a strong correlation.

like the negative reviews on amazon of scented candles...


 
Posted : 23/03/2023 5:12 pm
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I’m assuming she didn’t have a shingles vaccine? Would that be appropriate for the future?

I / we didn't know this was a thing. Off to investigate - Covid vaccine has been very good (although not perfect!), so....


 
Posted : 23/03/2023 5:21 pm
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During the earlier trollstorm I said I wondered if the lockdowns were all necessary* and that the impact was not inconsiderable in other effects.

I think the debate is needed, so not sure what I think of this piece and politicising it as 'now the left is rewriting the history'

* should have implemented the first one earlier, later ones possibly not as effective or necessary.


 
Posted : 23/03/2023 7:00 pm
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I love the way these idiots think COVID is some globally coordinated conspiracy.

I can barely get anyone to agree on anything at work yet somehow all the world's politicians, medical staff, scientists and pharma companies have all managed to agree on this mass conspiracy with ease


 
Posted : 23/03/2023 7:05 pm
StuE and Poopscoop reacted
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From seeing his posts, he is an expert in a very narrow field only, and associated with the much discredited (appallingly inaccurate) computer modelling of this pandemic

Thanks but you are mistaken. Whilst I served on SAGE/SPI-M, I didn’t produce any of the “discredited” modelling, only valid statistical inference for near-term forward projections using time series stats. These analyses were used as a counter view to much of the models to hilight their uncertainty and limitations. As it turns out, the projections as gauged by area under the curve of deaths wasn’t that far out.

I did however work for two years developing an approved medicine for COVID during my day job. And have spent twenty years working on the development of new medicines, many in infectious diseases and immunology.

As for vaccine efficacy, the relative risk reduction seen with mRNA vaccines was unprecedented. Without doubt they have vastly reduced the global morbidity and mortality of SARS-COV2. That people are being infected by variants, doesn’t not detract from the burden of morbidity and mortality. I wish I’d had mine before I met SARS-COV2 the first (and second) times.

@mat_outandabout, I hope your wife feels better soon, she ought to receive the chickenpox booster vaccine to help prevent shingles. And of course antivirals or possibly sotrovimab for COVID infection, and/or Evusheld (which has to be paid for privately) for prophylaxis. Sadly the virus has moved to evade protection by Evusheld, but AZ has the SUPERNOVA trial open for Evusheld v2, if she is eligible.


 
Posted : 23/03/2023 7:06 pm
PeteW, verses, twistedpencil and 5 people reacted
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Vioxx

is an interesting case. Whilst some of the antics of the company were inexcusable, and rightly punished, this is an example of unknown science. Vioxx and other cox2 inhibitors block one enzyme, but not cox1. That means it relieves pain and inflammation but doesn’t hit the gut. An increase in cardiovascular events (mainly heart attacks) was noted, and vioxx withdrawn Voluntarily (with blockbuster sales at the time).

Subsequent scientific study has shown that nonspecific cox inhibitors carry a similar risk (hello ibuprofen), and of course that the patients with inflammatory diseases also carry additional risk. The question is really benefit-risk, and it’s likely vioxx has the same, perhaps better, benefit risk compared with ibuprofen. Science is not certainty.


 
Posted : 23/03/2023 8:22 pm
kelvin reacted
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@TiRed - you don't need to respond to the trolls. Those of us who've been around long enough appreciate your work and the info shared on here in the darkest of times.


 
Posted : 23/03/2023 8:59 pm
fasthaggis, felltop, AndrewL and 5 people reacted
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seconded

If only I understood more than every second word 🙂


 
Posted : 23/03/2023 9:00 pm
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I think the debate is needed, so not sure what I think of this piece and politicising it as ‘now the left is rewriting the history’

* should have implemented the first one earlier, later ones possibly not as effective or necessary.

There's no doubt lockdowns reduced the impact of the virus, we need to learn what we can from it to judge how any future lockdown* could be more effective at reducing spread and less damaging economically etc.

*for any future pandemic


 
Posted : 23/03/2023 9:49 pm
Poopscoop reacted
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Of course I don't, but Vioxx is a very interesting story quite close to my heart (no irony intended) and worthy of discussion - it is informative about drug development in general. Huge push to find a better class of medicines, eventual success. Observation of a safety signal, likely driven by BETTER pharmacovigilance (how population based safety finding should work), and eventual removal of the class. Only to subsequently find that the nonselective drug (ibuprofen), widely used, probably has the same safety liability. Finding new medicines is hard! Finding relatively rare safety signals in populations is also hard. That a signal was spotted for the AZ/Oxford vaccine so quickly is a measure that the pharmacovigilance systems work. We should be proud of that.

@tjagain ibuprofen, diclofenac, aspirin, naproxen hit two targets, one for pain and inflammation (good) and the other in the GI tract for mucus secretion (bad, GI bleeds). A drug that just hit the pain would be a great drug. That class were selective as they hit only one of the two targets. Pharmacologists love selectivity. Vioxx was the only one approved in the US. Hitting that pain target may, however, also increase cardiovascular risk and that was why the selective drugs were withdrawn. Only subsequently were the safety signs noted for the common NSAIDS too.


 
Posted : 23/03/2023 10:45 pm
kelvin and Poopscoop reacted
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I was joking dude 🙂

But thanks anyway 🙂


 
Posted : 23/03/2023 10:49 pm
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I love the way these idiots think COVID is some globally coordinated conspiracy.

One of the explanations of why people like conspiracy theories is that it is, for whatever reason, easier for someone to ascribe something to a person or group decision making than to think it was just some virus jumping the species gap.
The theory is it means it is at least within humanities control however malicious that subset of humanity might be rather than just randomish chance.


 
Posted : 23/03/2023 11:25 pm
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Long Covid study in Scotland

I'm not sure that teaches us much, though acknowledgement that it exists, and that it affects so many people, might inform our development of care pathways and treatments.


 
Posted : 24/03/2023 12:07 pm
 kilo
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Just tested positive, second bout of it. Feeling pretty crappy, I blame George Soros.

(I don’t really)


 
Posted : 24/03/2023 12:34 pm
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