Am not an avid viewer but seems to me that a most of the humour in the one liners uses Senor Sheen’s real life and personality as a crutch for irony or to make it tongue in cheek believable.
Just can’t see it working the same with anyone else, then again Doctor Who is a good example of where you can’t see it being the same and while it never is the new guy makes it watchable (or not) with the freedom to express his own personality.
Not sure they picked the right replacement, but have never seen him in anything. So, if they just have this new guy reading the same script it will bomb, if they introduce a new character might work, depends if he’s funny.