Just follow one of the other group of lads/girls dressed up as nuns/fairies etc.!
Asking in terms of hotel/b&b, pubs or sightseeing?
Town centre is fine. Maybe best to avoid the Bigg Market. Loads of decent bars around the central station these days. The quayside was decent but seems to have gone quiet in the past few years. To be honest it’s ten min walk from end to end of town centre so not unknown to do a crawl from Quayside up to Haymarket (near unis).
Jesmond is nice too, plenty of bars but not sure what the bouncers are like with stag dos. Few b&bs too so a short stagger home.
Probably avoid any other outer area. Some of them get a bit tribal, and really just local pubs for local people. Gosforth is fairly safe but probably wouldn’t make the (10 min) trip to go drinking there.