I’ve got the 3rd set of bottle bosses under the downtube of my road/tourer (Dawes Galaxy FTW).
I’ve got one of the plastic Lezyne Flow cage with a Decathlon plastic tool caddy/bottle in it, seems to be solid enough.
It holds 2x inner tubes (28×1.24), 2x Pedros tyre levers, patches, multitool, spare chainlink, C02 canister and a tiny inflator plus a few examination gloves jammed in there for oily repairs at the roadside and to stop everything from rattling. I also have a small pump attached to the frame.
The cage grips the bottle well although I have wrapped a couple of turns of black insulating tape around it to keep it in place just to be safe. It looks alright as the whole assembly is black.
Only gets used on road/cycleway so doesn’t get shaken about as much as an MTB would.