- Experience with Azathioprine?
This is more of a moan than looking for anything helpful 🙁
I started on 100mg of azathioprine about 3.5 weeks ago. After a couple of days I got really tired, lack of appetite, nausea, hunger, lack of concentration…but that passed into the third week, so on Friday I upped the dose to the full whack of 175mg. Was fine for a few days and guess what… tired, lack of appetite, etc, etc. 🙁 I’m sure it will pass as my body gets used to it, but it’s a horrible feeling in the meantime.
Also, when the side-effects had started to wane, I was finding that I wasn’t sleeping very well and getting restless in bed. It’s not listed as a side-effect…wondered if anyone else had this.
Anyway, I really **** hope this stuff works in the end!Posted 7 years agobeejSubscriber
GF (who’s also a pharmacist) has been on it for 5 years… 100mg initially, then reducing to 50mg fairly quickly, now alternating 50/25mg. She has nausea initially but was also on steroids, so she adjusted things so she had steroid in the evening and aza in the morning. Then again, she was also on about 3 other things at the time too.
She didn’t have any sleep problems.
Are you on anything else? Might be worth talking to a pharmacist/doctor about whether you can adjust things to reduce side effects.Posted 7 years ago
No, I’m not on anything else, thankfully. al2000, 10 years constantly? Or do you go into remission with your symptoms and come off it for a while?
The sleep problems to be honest aren’t too bad – I still get a good 6 hours or so, and I certainly don’t have the lethargy I used to (side-effects notwithstanding!) so not particularly worried.
Can I ask what you guys/girlfriends use it for? I’m hoping it’s going to clear up a load of symptoms which may/may not be Crohn’s Disease!Posted 7 years agothejesmonddingoMember
If you havent got a definite diagnosis,azathioprine is not always a good drug to play around with,have you seen a gastro-enterologist? IIRC we used to start Crohn’s patients on 50-75mg and work up fairly slowly titrating against symptoms,increasing dose every2-4 weeks,your consultant may use it differently.Posted 7 years ago
I’m sorry kit,I’ve just reread your first post,are you self-medicating with azo? The inflammatory bowels diseases are a real speciality within medicine,and I would advise you to see a gastro-enterologist,for a definite diagnosis,and a coherent treatment plan.Posted 7 years ago
3 years of investigations through the GI guys at the Western General in Edinburgh, including recently investigations by a dermatologist and a dental health professional. I’ve had 4 tail end biopsies + sigmoidoscopies, a colonoscopy, two MRI/CT scans and most recently a seton drain installed to keep open a perianal fistula. Dermatologist is fairly sure I have Crohn’s, dentist sure I have orofacial granulaumatus (sp?), so being given the go-ahead by my GI consultant to try this out.
So no, not self-medicated at all! 😉
edit: just saw your post Ron – I’ll drop you an email sometime, thanks!Posted 7 years agoal2000Subscriber
Blimey, sounds like you’ve not had much fun at all..
Been on it 10 years constantly, but with one 8 month stretch off it just to see what happened. What happened was that my Crohns started to flare (which has always been a slow process with me), so it was quickly back onto it.
Only problem I’ve had with the azathioprine is increased susceptibility to infection. Not been a real issue, but has been more of a problem since my daughter was born. Currently playing with dosage to find the lowest possible maintainance dose.
Hope you feel better soon, and hope that it works for you. Made a huge difference for me.Posted 7 years agoTroutWrestlerMember
I took azathioprene to suppress my immune system to see if it helped to prevent my eczema flaring up. While my skin was ‘marginally’ better, the real difference was I came down with endless colds and chest infections. I work as a Teacher in a secondary School, and the daily exposure to DIRTY teenagers (LOL) made continuing on the meds a no-no.Posted 7 years ago
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