Echo qwerty
52mm for me too, provided you have chainring, crank and heel clearance on the frame.
52mm is already lined up far closer to the smallest sprockets so I wouldn’t want to be pushing the chainline any more to the drive side. People say they notice no difference but ride a SS with perfect chainline then go back to 55mm and the largest sprockets and tell me it is smooth.
The plus 6-8mm Q-Factor on cranks is a definite no go for me too with sensitive knees. I couldn’t adjust cleats/ pedal axles/ etc to get comfortable with even the lowest Q-Factor 55mm chainline cranks. XT cranks are already wide as it is. Maybe you won’t notice.
If your current setup has the hub spaced correctly for Boost width hub then choosing 52 or 55mm chainline should work. Bikes like a Trek Top Fuel or Scott Spark have 148 Boost rear ends and 55mm chainline cranks