We will at least protect those in nursing homes a lot better this winter.
Yes let's hope so.
The passive antibody vaccine TiRed, what are the likely benefits to my mother, or myself as the only person that could realistically infect her?
Upside is all the protection of a vaccine for probably one or two jabs per year. It gives you the same or even better protective antibodies rather than asking your body to make them. The antibody I'm working on is extremely potent, came from a patient of SARS-CoV1 and is likely to be superior to the vast majority of antibodies you or I make. These will be used to treat severe infections, and provide protection to the at risk/vulnerable like you and your mother.
People fail to realize that just making antibodies isn't enough. They have to neutralize the virus and they have to be sufficiently potent and abundant. Most antibodies you make won't be. Indeed I didn't even make enough for serum donation myself!
Oxford and Imperial have some good PR teams for their vaccine efforts. Pharma companies deliver billions of doses of highly tested and highly regulated vaccines per year using precedented technologies, platforms and distribution networks. I'll leave you to draw your own conclusions. The AVERAGE time between identification of a new pathogen and availability of a marketted approved vaccine is... thirty years. There are no approved vaccines for any coronavirus.
Antibodies will be available next year.
do yer tie up you scruffy 6th former
We were warned in the 1970's. Why did no one listen?
Antibodies will be available next year.
So these antibodies..Are they in affect a temporary vaccine? Ie you'd need to get a few doses every year to stay protected?
And another daft question.. Do these need to be 'harvested', or can they be grown in the lab and as such have unlimited doses available.
So these antibodies. Are they in affect a temporary vaccine? Ie you’d need to get a few doses every year to stay protected?
You'll need continuous protection - possibly one or two small jabs per year would not be unreasonable. I suspect that any vaccine will also require annual jabs - a bit like influenza vaccination, but not quite for the same reason (flu changes its coat each season).
they are made in bioreactors using mammalian cells and DNA transfected, just like other therapeutic antibodies. About 100k doses per batch.
BCC didn't get blojo's memo "lock down is over".
At the risk of sounding a bit right wing/mental.....it really ****ing pisses me off that huge numbers of those pricks at the beach will be getting paid through the furlough scheme....if they're going to blatantly disregard social distancing and health advice, then get the ****ers back to work and off the taxpayer payroll ffs.
Meanwhile, more Darwinism in progress
Prick on the beach on the BBC site getting interviewed. Basically admitting it going to cause a second wave but it doesn't really matter as he doesn't know anyone who's had it.
Selfish xxxx, part of me hopes he gets a dose and he spends a good few months feeling sorry for himself in recovery.
At the risk of sounding a bit right wing/mental…..it really * pisses me off that huge numbers of those pricks at the beach will be getting paid through the furlough scheme….if they’re going to blatantly disregard social distancing and health advice, then get the * back to work and off the taxpayer payroll ffs.
Yep, that does sound a bit odd - they're on furlough because there isn't work for them to do. Gov't health advice is that outdoors, people can go where they want. And in 30 degree heat, they're going to the beach! I've been to the beach a month back, social distancing was totally possible. Chose to avoid Bournemouth/Sandbanks as it's ALWAYS rammed and less for families, more for boozers. Don't think there's anything different now about how the beach gets left than in normal times, sadly. Where I go, people tend to respect the environment more and take their crap home.
Water just off that beach is probably 10% piss by now. Happy holidays.
Basically admitting it going to cause a second wave but it doesn’t really matter as he doesn’t know anyone who’s had it.
To be fair, when we started coming out of lockdown a month back people said the same thing, also when it was hot and beaches were rammed. Correct me if I'm wrong but I haven't seen lots of evidence of mass transmission from this type of environment. Secondary outbreaks I have seen reported are from meat processing, child processing and drink processing.
those pricks at the beach will be getting paid through the furlough scheme….if they’re going to blatantly disregard social distancing and health advice, then get the **** back to work and off the taxpayer payroll ffs.
Although I understand why you're frustrated, those Furloughed workers don't have jobs to go to and have families to support. A very large percentage of them won't go back to a job. Focus on the real issue not your jealousy about how people are being paid.
Police are moving in to clear the beach apparently but are "overwhelmed".
Not jealous at all mate....my gf is furloughed....I'm self employed so have picked up some nice 'free money'. I just find it frigging mental that this is being allowed to happen....my frustrations are more at the government than the morons on the beach. Although they can rather aptly get in the sea.
I can't help but agreed with you there Tom B, it beggars belief!
...and also buried in the new - COVID19 cases on the rise in UK and Europe.
…and also buried in the new – COVID19 cases on the rise in
UKEngland and Europe
FTFY.
Will the beach stuff cause a second wave though?
If theyre not sharing immediate & especially enclosed space; toilets, bars, undistanced public transport
how will the virus be passed?
https://www.ecdc.europa.eu/en/covid-19/latest-evidence/transmission
Working from home or furloughed looks more fun than a shift at my NHS lab today at 30°c wearing a mask for the whole shift....
I still wouldn't swap with those Muppets on the beach though.
Now off to a "preparations for the second wave" meeting ☹️
child processing
What did I miss? 🤔
I mightn’t be able to survive the rage felt if get to see the inevitable fake surprise required of Bozo as he takes the stage (over this nudged situation at beaches and soon bars)
As he goes live and pretends to ‘reprimand’ his supportive hordes tut tut, caw, caw. Smirk, smirk. ****s sake 😡
Time to take a break from all media methinks. Just discovered on fb that my best friend’s mum died. Funeral is at her home town (topically, ironically - also a popular beach) this Saturday 😢
Maybe I'm missing it, but since we no longer have a daily update from the UK Government, has the BBC also stopped reporting the latest infection/death rates? They are still available on BBC Scotland, BBC Wales and BBC NI.
It's in here:
BBC News - Coronavirus: Prof Chris Whitty warns public over gatherings in hot weather
https://www.bbc.co.uk/news/uk-53185386
I just check here daily:
https://coronavirus.data.gov.uk/
It’s in here:
BBC News – Coronavirus: Prof Chris Whitty warns public over gatherings in hot weather
Yeah, it is today. And tomorrow it'll be in some other article.I guess I've just got used to seeing it as a specific item on the BBC Scotland page. The BBC obviously doesn't think that 138 deaths in England the past 24 hours is newsworthy, whereas 2 in Scotland is.
Goand have a look at that link:
https://coronavirus.data.gov.uk//a >
Then the "Total number of lab-confirmed cases in England by specimen date" using the "Table" option. Look at the rise in cases since June 18.
Holy crap.
kimbers
SubscriberWill the beach stuff cause a second wave though?
No. TBH there's not many things that in isolation can. But it's symptomatic/emblematic of the behaviour that's happening all over the country which could. Well, if we weren't still in hte first wave anyway.
Kryton, don't think you've understood that table.
Kryton, don’t think you’ve understood that table.
Sorry, you are correct what a numpty. I'll go back to sleep...
Trending to an asymptote of perhaps 1-300 cases/day, perhaps 1-3000 cases per week, and hence about 10 deaths/week. That’s endemic. At such small numbers and spatial spread, it’s impossible to really predict when and if it will die out. Or whether there’ll be a brief flare up.
Lockdown was a once only action. It’s helped of course, but I don’t think eradication is going to happen. Play the long game. I still believe social interactions have changed and it will be perhaps 18mo to be back to normal. Whatever normal looks like.
Trending to an asymptote of perhaps 1-300 cases/day, perhaps 1-3000 cases per week, and hence about 10 deaths/week.
How long before it's down to 10 deaths per week in the UK?
Well I though about 10/day from July. Once the numbers get to such low levels, prediction is really not possible. But if I had to guess, September. Maybe.
Sweden is the example to which we will eventually have trend to. Other countries may see resurgence and importation of cases. Such as New Zealand.
Or it could die out, we have no cases and a challenge to develop treatments and vaccines for a pathogen that’s gone. That would be nice.
Thanks for taking the time to give a detailed reply to my question. I feel a bit better informed now and I'll dare to hold some hope for next year.
Thanks again.
As ever...
^ 😂
One of my friends from the South Coast is going mental at the newspaper headlines:
No prizes for guessing where they took their family yesterday. They're on their last chance before I unfriend them, especially as a lot of their friends round them are defending each other for going to the beach.
So much for that famous British Common Sense.
As ever, the problem with common sense is that it isn't very common.
It seems that an surprising number of people are presenting at hospitals having had a symptom-less infection but with dangerously low oxygen saturation (levels that would normally make you unconscious) and concomitant damage to the lungs. Worth considering getting a sats monitoring machine (50 quidish).
There is potential for bed-blocking issues as some care home are refusing to take back geriatric patients, 25,000 of whom were passed on to the hospitals.
So much for that famous British Common Sense.
Uncommon sense,common sense is overrated IMHO.
Numpties flock to beaches in Pandemics, so you need stuff in place to mitigate that and make it less of a problem.
Still it'll make a good news story to hide the other delights.
the problem with common sense is that. . .
. . it's learned behaviour from experience, no one is born with it. Yesterdays beach goers had the exams on the sand, the learning comes in around 3 weeks. Deferred experiences are always the best.
The scenes on the beach and the other irresponsible behaviour was all predictable. Johnson knew what would happen when the relaxation was announced, but his policy is just to take a gamble that the worst is over. If he gets away with it, the public will be happy to have their freedom. If things go wrong, he'll simply say "I told people to behave themselves". It's a complete absence of leadership.
Or its more "behavioural science" from Bummings.
Lots of people are clearly going bonkers, tease them that the relaxation is coming "soon" and turn a blind eye when a few go ahead with it before time.
kimbers
Will the beach stuff cause a second wave though?
Well some will go to the beach and not catch anything... they will be validated and not bother anywhere else.
Some will go to the beach and catch CV and then spread it .. some will be asymptomatic or have a mild "flu" and they too will be validated... they will probably use that validation as a excuse to then pressure and infect more people .. look gran we all went to the beach yesterday and we're all fine...
Some will go to the beach, catch CV then spread the virus as above and die or gran dies but most won't associate this with going to the beach
Dunno quite what to make of this.
Covid-19: MPs reject calls to routinely test health and care workers