Forum menu
Pfizer or Astra Zen...
 

[Closed] Pfizer or Astra Zeneca vaccine ?

 diz
Posts: 79
Free Member
Topic starter
 
[#11650461]

If given the choice of the 2 vaccines which would people take and why?


 
Posted : 01/01/2021 7:10 pm
Posts: 8469
Full Member
 

Would you refuse one or the other?

Do you know which manufacturer of flu jab you get? Who makes your cancer drugs?

We are all desperate for knowledge but I think we are all trying to be too clever here.


 
Posted : 01/01/2021 7:15 pm
 db
Posts: 1927
Free Member
 

I think the BioNTech, Fosun Pharma, Pfizer vaccine. The RNA type seems logical to me.
https://en.m.wikipedia.org/wiki/RNA_vaccine

However I will take whatever I’m offered!


 
Posted : 01/01/2021 7:17 pm
Posts: 0
Free Member
 

It’s not the Matrix! I doubt we’ll even have a choice 😉
I’ll take the one that’s available soonest please.


 
Posted : 01/01/2021 7:18 pm
 db
Posts: 1927
Free Member
 

Oh and more info here if people want to read about it;

https://www.who.int/emergencies/diseases/novel-coronavirus-2019/covid-19-vaccines


 
Posted : 01/01/2021 7:18 pm
Posts: 13811
Full Member
 

If given the choice

I doubt you will get this.

Had a eye rolling discussion with someone not wanting to have as they didn't know possible side effects. I asked them what the side effects of paracetamol and ibuprofen were, they didn't know but declared them both safe as you can buy them without prescription. Ho hum..


 
Posted : 01/01/2021 7:21 pm
Posts: 5830
Full Member
 

Not commenting on the vaccines as not allowed (work for az).
But paracetamol would likely not be approved now if it was asked as its toxicity would be too high for non prescription medicines


 
Posted : 01/01/2021 7:25 pm
 pk13
Posts: 2734
Full Member
 

Not fussed just bang it in my arm please.


 
Posted : 01/01/2021 7:28 pm
Posts: 5672
Full Member
 

I doubt anyone will get a choice TBH. Maybe if you paid privately at a clinic. Any kind of state organised vaccination program will just have what’s available in that area.

FWIW I’ll have the vaccination as soon as it’s offered.


 
Posted : 01/01/2021 7:32 pm
Posts: 14707
Free Member
 

@grahamt1980, AZ or P? No comments needed... 😉


 
Posted : 01/01/2021 7:36 pm
Posts: 1083
Full Member
 

AZ for me. Pfizer have a history of making medicines with unexpected side effects that are hard to deal with.


 
Posted : 01/01/2021 7:41 pm
Posts: 7279
Free Member
 

AZ for me. Pfizer have a history of making medicines with unexpected side effects that are hard to deal with.

I'm not going to rise to that.


 
Posted : 01/01/2021 7:45 pm
Posts: 5830
Full Member
 

Even answering that would be enough. At the moment I would have whichever one is going to get to me first.
After that. . . . Will see


 
Posted : 01/01/2021 7:57 pm
Posts: 1083
Full Member
 

AZ for you as well then mefty, to be on the safe side 😀


 
Posted : 01/01/2021 7:57 pm
Posts: 7044
Full Member
 

Both, one in each arm. Then down the pub.


 
Posted : 01/01/2021 8:25 pm
Posts: 0
Free Member
 


 
Posted : 01/01/2021 8:39 pm
Posts: 0
Free Member
 

If given the choice, the AZ vaccine because it's manufactured in the UK so has lower vaccine miles 😉


 
Posted : 01/01/2021 8:47 pm
Posts: 16175
Free Member
 

There won’t be any choice. However look at the details

Pfizer has to be kept in a very cold fridge, Oxford does not. Now that’s not to say they can’t defrost it etc, but which centres have been set up first, and which have the cold fridges, or more relevant likely not to.

Isn’t one 90% effective, the other 70%?


 
Posted : 01/01/2021 8:47 pm
Posts: 232
Free Member
 

Had the pfizer last week. Noticed no side effects other than a slightly sore arm.


 
Posted : 01/01/2021 8:49 pm
Posts: 13349
Free Member
 

Whatever I'm given will do. The calculator predicted I would be getting the jabs in October/November, which seems a little slow.

Edit I'm 58 with no real underlying health issues.


 
Posted : 01/01/2021 8:51 pm
Posts: 41869
Free Member
 

Isn’t one 90% effective, the other 70%?

Assuming they inhibit transmission by the same percentage it's kinda moot, simplistically modeled as everyone getting the vaccine on the same day, then after a couple of weeks you reach an infection rate so low as to be effectively zero anyway (4 days from exposure to symptoms at which point you should isolate, so an average of 2 days), so if everyone had the 70% vaccine and the number remained ~1.2 thats (0.3*1.2)^7, the infection rate drops to 0.08% of what it would have been.

The flipside is, no one knows how effective they are at preventing transmission, the data doesn't exist yet (assuming they're comparable seems reasonable on the assumption that to be effective they result in a very low viral load).


 
Posted : 01/01/2021 9:13 pm
Posts: 2094
Full Member
 

I'll go for the AZ vaccine if I have the choice. 2nd choice the Russian Sputnik 🤔😉


 
Posted : 01/01/2021 9:17 pm
Posts: 14484
Free Member
 

You’d be utterly insane to not go with Astra Zeneca

No this has nothing to do with any shares we may have with AZ


 
Posted : 01/01/2021 9:19 pm
Posts: 453
Free Member
 

What ever I am offered.

Then prahaps the other one as well.


 
Posted : 01/01/2021 9:21 pm
Posts: 25943
Full Member
 

Isn’t one 90% effective, the other 70%?

Haven't bothered my arse looking for publications but I **THINK** that outcomes were a bit different too:
Tha AZ study(ies) gave all participants a set of full-on testing kits (deep-throat/up the nose & scrape the back of yr pituitary) to use every week. I believe that the Pfizer study waited for subjects to show symptoms before testing them.

If that's right, then Pfizer was 90ish% effective at preventng symptomatic infection, while AZ was 62-90% effective at preventing detectable infection.

[are the studies published now - do we have ^ that info?]

[[seems we sort of do. Pfizer study:
Confirmed COVID-19 was defined as having a positive RT-PCR respiratory specimen for SARS-CoV-2 AND at least one of the following: fever, new or increased cough, new or increased shortness of breath, chills, new or increased muscle pain, new loss of taste or smell, sore throat, diarrhea, or vomiting.]]


 
Posted : 01/01/2021 9:23 pm
Posts: 1305
Free Member
 

The most effective medicine is the one that the patient is happy to take...
As long as enough people get vaccinated it won’t matter which one they have...
Worrying about 62 vs 95% trial results is kinda pointless. They are both effective.
Doi- volunteered in the Oxford trial. Weekly swabs continuing...


 
Posted : 01/01/2021 9:29 pm
Posts: 814
Free Member
 

Just reading that they will try and match for second dose but can mix if necessary. So I think you will just be asked to line up and take what’s on offer.


 
Posted : 01/01/2021 9:33 pm
Posts: 3130
Free Member
 

Ideally I’ll have one that doesn’t contain part of the disease as being immune suppressed I would worry and I think they will too. I’ve not looked if either contain a live dose as I trust specialists and NHS to tell me which is safe for me. According to the calculator it’ll be March time.


 
Posted : 01/01/2021 10:20 pm
Posts: 13496
Full Member
 

The only person I know personally who actually knows this science rather than being an internet armchair expert says she'd prefer the oxford if given a choice, which is good enough for me.

I'll happily have whatever offered. And the sooner the better - only because if I get mine soon as a 10th priority (lowest) it means all those I love and care for more vulnerable than me will have got it even sooner.


 
Posted : 01/01/2021 10:29 pm
Posts: 7125
Full Member
 

Which one has the best 5G reception? I'll take that one.


 
Posted : 01/01/2021 10:29 pm
Posts: 20985
 

Given the organisational abilities of my GP surgery, I’ll be lucky if I get the TB one.


 
Posted : 01/01/2021 10:40 pm
Posts: 670
Free Member
 

If approved in time (March / April) I can see most getting the Janssen vaccine as single dose and can be stored at fridge temperature.


 
Posted : 01/01/2021 10:42 pm
Posts: 5392
Full Member
 

I'll take whichever one is being offered. As the Omni calculator thinks I won't get vaccinated until Dec 21/Jan 22 I'm not too worried about unknown side effects.


 
Posted : 01/01/2021 10:48 pm
Posts: 4417
Full Member
 

I'm up for any of the mRNA vaccines, just because I think the mechanism is cool.

The mechanism for other vaccines is also pretty cool though so I guess it's win-win.


 
Posted : 01/01/2021 11:39 pm
Posts: 2306
Free Member
 

Well, I’ve had the Pfizer one and haven’t grown anything extra, other than extreme grumpiness and an overwhelming intolerance for Covid conspiracy theories (unrelated to this thread btw!)

I guess my answer would be the Pfizer
One then?


 
Posted : 02/01/2021 12:10 am
 poah
Posts: 6494
Free Member
 

Ideally I’ll have one that doesn’t contain part of the disease

not going to give you any immunity to it then lol

just because I think the mechanism is cool.

Makes a mockery of the Eukaryotic translation pathway 😛


 
Posted : 02/01/2021 2:12 am
 hugo
Posts: 0
Free Member
 

Isn’t one 90% effective, the other 70%?

An oversimplification but a good point.

Would you refuse one or the other?

No, but that's moving the goalposts. The question is which one would you choose?

My answer would be either but would have a preference for the Pfizer one as it's been proved to have a higher efficacy. They have both be proven safe.

This doesn't have to be confrontational or polarising. It's a reasonable question.


 
Posted : 02/01/2021 5:32 am
Posts: 14484
Free Member
 

Ideally I’ll have one that doesn’t contain part of the disease as being immune suppressed I would worry and I think they will too.

Question.

Do not all vaccines work by imitating in one way or another the thing itself you are vaccinating against?


 
Posted : 02/01/2021 7:38 am
Posts: 0
Free Member
 

Is there any truth in this from the New York Times that Britain is adopting a mix and match approach? I can't believe they would? Surely some sort of clinical trial is required? Scary that they are saying 'if the first vaccine is unknown' This should never be the case surely?

Mix and match vaccine


 
Posted : 02/01/2021 1:24 pm
Posts: 20985
 

Seems just like something our fearless leaders would do (along with changing from 3 to 12 weeks between doses, to enable more people to get at least one jab...)


 
Posted : 02/01/2021 1:36 pm
Posts: 8469
Full Member
 

I imagine our world getting vaccination task force can’t actually keep tabs on who it has jabbed with what.


 
Posted : 02/01/2021 2:25 pm
Posts: 1305
Free Member
 

The the nytimes article, read the response I posted to it the first time someone posted it a bit up the thread...


 
Posted : 02/01/2021 2:56 pm
Posts: 3130
Free Member
 

THE FOUR MAIN TYPES OF COVID-19 VACCINE
There are four categories of vaccines in clinical trials: WHOLE VIRUS, PROTEIN SUBUNIT, VIRAL VECTOR and NUCLEIC ACID (RNA AND DNA). Some of them try to smuggle the antigen into the body, others use the body’s own cells to make the viral antigen.

Whole Virus = "both types use well-established technology and pathways for regulatory approval, but live attenuated ones may risk causing disease in people with weak immune systems"


 
Posted : 02/01/2021 5:53 pm
Posts: 12809
Free Member
 

Whichever is closest frankly, although it’ll be months and months before I’ll be offered one.

My wife was supposed to have her Pfizer one weeks ago, but we were in Wales and we have a seemingly laissez-faire attitude to rolling it out it’s been pushed back a couple of times.

On the plus side, we’ve had 150k confirmed cases in Wales, if for every confirmed cases there are 9 non-confirmed so it’s not a bad guess that 1.5 million people in Wales have had COVID, that’s about half the population, it’s also rising at 2k-3k confirmed cases a day, so that’s 20k ‘real’ cases, in a mere 75 days everyone in Wales would have had it at least once.


 
Posted : 02/01/2021 9:34 pm
Posts: 438
Free Member
 

Having the second dose in 12 weeks has a sound basis, the messaging has just been handled abysmally by Govt/PHE/NHSE as usual. The first dose in the Oxford trials gives around 50% immunity but 90% reduction in severe disease. Scaled up to and more of a population this has a significant impact on disease severity and the burden in hospitals (which obviously have to treat a lot of other conditions from which people die). I’m booked to get the Pfizer jab next week and happy to wait a longer for the second jab and do my bit.


 
Posted : 02/01/2021 10:09 pm
Page 1 / 2