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Menopause and poten...
 

Menopause and potential family destruction

 myti
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We're all living a lot longer post menopause and expected to be able to work longer too. I used to think I need to do everything the 'natural' way but after experiencing life and relationship limiting peri symptoms and discovering that the newer, body identical hrt treatments exist I changed my mind and have no qualms about cancer risks. Those were hugely overblown and were also based on the old types of hrt. The newer types show very little or no evidence of increased risk as long as you are not one of the few unlucky people to be genetically prone.

"Many women worry about breast cancer when taking HRT, but most types of HRT do not actually increase the risk of breast cancer. Some studies have shown that women taking combined HRT containing both estrogen and a progestogen (which is a synthetic progesterone) may be associated with a very small increased risk of breast cancer.

The increased risk is related to the type of progestogen in the HRT and not the estrogen. Taking micronised progesterone (the body identical progesterone) has not been shown to be associated with an increased risk of breast cancer.

Even for women taking the synthetic progestogen, the risk is very low and is actually less than the increased risk of breast cancer associated with drinking a couple of glasses of wine each night, or from being overweight. No studies have shown that any type of HRT increases the risk of a woman’s death from breast cancer.

If you have had a hysterectomy in the past, and are just taking estrogen without a progestogen, you actually have a lower risk of breast cancer than if you did not take HRT at all. There is also no increased risk of breast cancer in women who take any type of HRT when they are under the age of 51 years.

If you take estrogen in tablet form, you have a small increased risk of developing a blood clot, but this risk is not
present if you take estrogen through the skin in a patch, gel or spray"

Biggest killer of older women is heart disease (which is reduced with hrt)and then other things like osteoporosis leading to hip breaks mean much reduced quality and length of life. So by all means everyone make their own choice but just like when deciding whether to get the COVID vaccine it required a risk reward assessment the same should be considered with hrt especially with new treatments and updated knowledge. A lot of GPS still have pretty outdated ideas so even seeking professional advice can be a potscode lottery.


 
Posted : 27/08/2023 3:34 pm
thinksta, ART, anorak and 1 people reacted
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Taking micronised progesterone (the body identical progesterone) has not been shown to be associated with an increased risk of breast cancer.

Just to clarify, that still means that it could still be associated with an increased risk of breast  cancer, indeed, medically speaking, it would be surprising if it wasn't in time.

Micronised progesterone almost certainly hasn't been used in enough patients for long enough for the risks to show up yet. It takes years for increased risks to show up in the data, especially if they're relatively small.


 
Posted : 27/08/2023 3:50 pm
thinksta reacted
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Second, it’s more about how women would feel if they then developed cancer.

And the problem with this is of course that the cancers are quite common, and the increased risk demonstrably small, but everyone who gets cancer will suspect that it wouldn't have happened without the HRT, even though this belief is obviously false for a large majority of them.

But, you know, just about everything causes cancer at some level. I'm sure that none of us manage to avoid all known risks, and most of us indulge in major and well-known ones like alcohol, red meat and other dietary factors.


 
Posted : 27/08/2023 3:53 pm
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No studies have shown that any type of HRT increases the risk of a woman’s death from breast cancer.

That's a disingeneous way of putting it when studies have clearly shown an increased breast cancer risk, but the survival rate from breast cancer is high. It would be very difficult to find astatistically proveable link using only cancer death stats.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31709-X/fulltext

Like many people of my age I know a good few breast cancer survivors and the lasting effects of the treatment they have endured conbined with the psycholgical impact are considerable. Objectively according to that Lancet article you are playing a numbers game, are the benefits of HRT (if any depending on the person) worth a 1/25 - 1/200 chance of getting breast cancer if you take HRT of some type for between five and ten years.


 
Posted : 27/08/2023 4:01 pm
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But, you know, just about everything causes cancer at some level.

It depends what you mean, exactly, by that statement?

First, it's not everything. Very few plants, if eaten and not overly processed, are associated with an increased cancer risk, in fact they're mostly protective.

Second there are substances that are toxic at any dose. Tar in cigarette smoke, alcohol being two most commonly ingested.

Third is that there are some substances that are carcinogenic if consumed in large amounts (above the toxic threshold), but that don't seem to have an increased risk if consumed at moderate levels (below the toxic threshold), such as red meat.


 
Posted : 27/08/2023 4:03 pm
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A lot of GPS still have pretty outdated ideas so even seeking professional advice can be a potscode lottery.

I have heard this from women I know - very variable response from GPs

Is this something that should be done thru specialist clinics?


 
Posted : 27/08/2023 4:09 pm
kelvin reacted
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Third is that there are some substances that are carcinogenic if consumed in large amounts (above the toxic threshold), but that don’t seem to have an increased risk if consumed at moderate levels (below the toxic threshold), such as red meat.

Why do you think there is a threshold for red meat?

Most cancer research is based on a quasi-linear model (perhaps something like log-linear) implying the absence of a threshold, the risk just increases with the level of consumption. Of course this is hard to prove, as the increase in risk may be undetectable for very small doses. That doesn't mean the risk is zero.

Regardless, the proven threshold for meat causing increased rates of cancer is not very high. A quick google suggests that 50g per day causes a clear rise in colorectal cancer rates.

But yes you're right I was much too broad saying "just about everything". I should have said something like "lots of things that many people eat and do routinely".


 
Posted : 27/08/2023 4:17 pm
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Is this something that should be done thru specialist clinics?

No. It's a reason to prioritise recruiting and retaining good quality GPs and reducing our workload so that we can provide a better cost effective service.


 
Posted : 27/08/2023 4:20 pm
twistedpencil, ratherbeintobago, Bunnyhop and 4 people reacted
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Most cancer research is based on a quasi-linear model (perhaps something like log-linear) implying the absence of a threshold, the risk just increases with the level of consumption. Of course this is hard to prove, as the increase in risk may be undetectable for very small doses. That doesn’t mean the risk is zero.

Now try convincing the pro-nuclear people on this forum and elsewhere of that. 🙂


 
Posted : 27/08/2023 4:34 pm
 ART
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So if you had a family history of both breast cancer and osteoporosis what would you do, ART?

I have no issues with women choosing HRT and there are often good medical reasons why they would as other women have said. Perimenopause/ menopause is in many ways a 'barometer of health' that can reveal and amplify underlying health issues so there's every reason to come at this stuff holistically if you can.

I do have family history, but I focus on the things I can control. That means eating the right food, paying attention to gut health, taking the best supplements, lifting heavy, not drinking alcohol, maintaining a healthy circadian rhythm and avoiding [unnecessary] stress  as best I can - you know, like getting sucked into threads like this on STW - 😉


 
Posted : 27/08/2023 6:31 pm
AD reacted
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ART

your post have been interesting to me.


 
Posted : 27/08/2023 6:35 pm
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Two things.

1) I'm loving Kramer's contributions to this thread.

2) "Today, we had the most ridiculous exchange of words about what pants I wanted for Christmas – in August. I admit I responded with some incredulity. I would laugh at how puerile it all was if it wasn’t a perfect microcosm of our difficulties." This concerns me deeply. Hormones aside I've seen this movie before and it ended with me with a golf-swing related concussion.


 
Posted : 29/08/2023 4:20 am
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Christmas pants, i raise that one with "two tins of paint"

Other half " we have two tins of exterior paint that are the same colour but different"

Me "we only have one tin of exterior paint"

Other half "no we have two"

Me goes to shed fetchs one tin of paint.

Other half "wheres the other tin"

Other half "you must have thrown it out"

Me "yes i must have" returns paint to shed along with will to live Knowing full well there has never been two tins.

I can post this type of shit every day.


 
Posted : 29/08/2023 4:33 am
el_boufador reacted
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The osteoporosis information is interesting. I didn't take HRT and got away 'lightly' with very few menopausal symptoms, instead going down the 'doing lots of exercise' route (I stress this does not work for everyone). A few years later I had a fall (running down a hill and slipped, landing heavily) and broke my hip, this incident has really affected my life in so many ways. Had I known about HRT (there was very little info around then) maybe I would have gone onto it to prevent osteoporosis.

Kramer - it's also not always possible to step away from someone in one's life that causes grief or is toxic (in my case a female relative). But can I just say your advice on this thread has been helpful in so many ways.


 
Posted : 29/08/2023 3:17 pm
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@Bunnyhop, you're correct, and that can be a very hard situation to be in. It can help to name it though.


 
Posted : 29/08/2023 3:32 pm
Bunnyhop reacted
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Thread resurrection, but my wife and I are on absolutely complete meltdown at the moment. Divorce is knocking on the door. I can not do or say anything right. It’s an absolutely horrific situation currently. I have never been so upset in my life, I didn’t know a 39 year old could cry as much I have done recently. It’s so sad, our twins are two. I love them dearly. It feels like a helpless situation.


 
Posted : 07/01/2024 8:58 pm
reeksy, jamj1974, MoreCashThanDash and 7 people reacted
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ed , cant comment on your exact situation but having had twins.... its freaking tough!

if indeed its a menopause thing then, at be least for us my wife got through it


 
Posted : 07/01/2024 9:02 pm
jamj1974, leffeboy, jamj1974 and 1 people reacted
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Thanks Kimbers. I did suggest to her perimenopause could be at play. Obviously she melted down at the suggestion but I thought I had to get it out somehow. She claims she then went to the doctors to discuss it, and she claims the doctor said they were concerned that someone would even suggest such a thing. If this was true I absolutely can not believe this was the response from the doctor. I’m just trying to look out for my wife because I care.

I honesty believe we will get divorced, but I can not stress how much I want to try and resolve it.


 
Posted : 07/01/2024 9:14 pm
jamj1974, leffeboy, matt_outandabout and 5 people reacted
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1
kimbers
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ed , cant comment on your exact situation but having had twins…. its freaking tough!

yes it can be, but it’s more down to the circumstances than the amount of children (parent to two 14 yr old girls and foster carer of one 13 yr old boy)


 
Posted : 07/01/2024 11:39 pm
jamj1974 and jamj1974 reacted
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Twins are hard work at 2, likely to have been lots of stress and complications with the birth, even if it went well. Have you considered post natal depression might be a factor?


 
Posted : 08/01/2024 12:50 am
 LAT
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i’ve not read the entire thread, but was wondering if you’d been to speak to your own GP, Edward?

i’ve just read the posts on this page and your wife’s behaviour doesn’t sound “normal”. i think you should discuss it with your GP. i say this only because it is what i would do.

good luck and best wishes 


 
Posted : 08/01/2024 6:53 am
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Thank you Lat. and a family member gave me the same advice yesterday. My mother thinks my wife is depressed, her brother (very empathetic and understanding) has she comes across as sad, and other people have commented. How do I tell her we think she is depressed without her yelling at me? How do I give her the insight to reflect within? All I want to do is help her, but I’m dammed if I do and dammed if I don’t.


 
Posted : 08/01/2024 7:18 am
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Really sorry to hear about this situation. I hope you find a solution.


 
Posted : 08/01/2024 7:51 am
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I have booked to see my gp today to discuss my wife and ways to help. Fingers crossed she can advise a way forward.


 
Posted : 08/01/2024 8:24 am
stwhannah, MoreCashThanDash, Mintyjim and 5 people reacted
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I posted a reply earlier that seems to have not made it, but it sounds like you are trying the right approach and have family on both sides who share your concerns.


 
Posted : 08/01/2024 8:30 am
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I have booked to see my gp today to discuss my wife and ways to help. Fingers crossed she can advise a way forward.<br /><br />

it’s worth writing some notes down of things you want to say. Then, if you get upset, you can refer to these to make sure you cover everything. 


 
Posted : 08/01/2024 9:10 am
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OP I’d suggest that you go and get some specialist relationship counselling to work out what your way forward is.


 
Posted : 08/01/2024 9:28 am
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Update. After posting this things seemed to magically get better, just a coincidence but a nice one.

Until last night.

We are on holiday and last night from nowhere she spent a couple of hours clinically discecting me to detail just how shit I am. I dont provide for family, I have anger issues, my parents are ****s, I'm a terrible lover, I have bad breath, i don't inspire our kids, all I care about is TDF (fair enough) she's stuck with me  and on and on and on and on.

Its a lonely place and I'm not seeking any advice. It's just strangely comforting sharing with friendly strangers.

My youngest is nearly 15 so I'll take the hit until he packs off to uni then I'll look after myself.


 
Posted : 20/07/2024 11:31 pm
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Sorry if this comes across as blunt, but if it has reached that stage, dragging it out for 3 years won't do you or your kids any good


 
Posted : 20/07/2024 11:47 pm
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One of my very good friends has just been through something very similar. He left, the divorce came through three weeks ago. He has 50:50 access to the kids. His life is immeasurably better and he only has his kids to answer to now. Maybe, just maybe, it is time you leapt. You will succeed. Time for self and child preservation.


 
Posted : 21/07/2024 12:10 am
 ctk
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We split when the kids were 10&12.  10y/o didnt even blink, 12 y/o was upset for a short period. We share childcare 50/50 (I have 4 nights she has 3).

I am much, much happier.  Still a bit scarred, she is doing ok too.  Kids are better than before!  Living in a miserable house is no fun.

Dog struggled mind ?  he likes everone in the same house but even he is used to it after 6 or 7 months.


 
Posted : 21/07/2024 8:37 am
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I dont provide for family, I have anger issues, my parents are ****s, I’m a terrible lover, I have bad breath, i don’t inspire our kids, all I care about is TDF (fair enough) she’s stuck with me  and on and on and on and on.

This is toxic behaviour OP.

It sounds like she’s goading you, trying to get a response out of you. It is wrong, and unless something changes it is likely to adversely affect your mental wellbeing.

Your children will be aware of it, and also of how you are responding to it.

She is not going to change.


 
Posted : 21/07/2024 8:49 am
ctk and ctk reacted
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Sorry to hear this OP.  I think you are right about getting out. If youngest is 15, plan to split after GCSEs, worked well for a mate and his kids.

On the back of this thread I finally forced a difficult conversation with MrsMC.  Pleased to say it led to things getting better - still a work in progress, but atmosphere a lot less tense, and my mental health is way better.


 
Posted : 21/07/2024 8:50 am
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