I have had a few major life events occur during the last decade, Dad dying, two kids born,business opening and failure, becoming professionaly qualified.
However, the thing which has had the biggest impact on me has been illness. Six months after my Dad died I developed stomach and gut problems. I was diagnosed with H-Pylori but the antibiotic didn't work. I took all sorts of stomach tablets over the next year but nothing was really working.
I took the idea in my head that I had cancer or was otherwise seriously ill. After going back and forward to my GP for over a year I went into some sort of denial and stopped seeking medical treatment. I got sicker and sicker, I could eat fewer and fewer foods, my ability to exercise was limited as exertion seemed to aggravate it etc.
Then, earlier this year when my business partner was acting bizarrely and I became seriously stressed, I stopped eating almost entirely and my stomach seemed to clear up. It has come back a bit recently but fingers crossed it's just over indulgence at Christmas.
The single biggest effect thinking I was ill had was to stop me thinking long term. I just lived for the day and that was the worst thing I could have done.
There were things I really wanted to do with my life which would require careful planning and putting groundwork in place over 3-5 years. I didn't do it because I genuinely thought my illness would get worse and could stop me working altogether.
My view is that you have little or no control over the future but for your own peace of mind, do everything within your power to create the future you want. It's doing the best by yourself that matters.