Funnily enough I bought one (Bamboo MTE 430 or 450?) last week.
Plug and play on my Vista Business PC (for use as a mouse etc), but had to manually enable tablet recognition in Services to get things like Vista text recognition/Office 2007 “start inking” tools. Had to do a bit of Googling TBH.
Tried on my Vista Business laptop, but it’s not liking it thus far. Haven’t tried on the MBP yet.
Standard Bamboo s/ware is okay – Dock is quite funky, if not gimmicky. Currently having a play with ArtRage 3.
The reason I mention the Business version of Vista is because I believe some versions don’t have some of the functionality.