Gearbox is likely to be fine, if you have a problem its more likely to be with the clutch and flywheel failing/slipping prematurely.
I had my old Audi S3 remapped (by Revo) when it was 1 year/10000 miles old, the standard clutch/flywheel lasted a further 10000 miles before it started to slip, so had a new (uprated) clutch and flywheel fitted, and it was fine for another 20000 miles before I sold the car.
I knew the clutch/flywheel was likely to not last long though, as I’d done a fair bit of research and there were a fair few people who had experienced the same.
I’d guess that if you’ve done your googling, and not uncovered many issues of clutch/flywheel failure on your car, it’ll be fine.
It made a massive difference to the acceleration, fuel economy was slightly worse (but not by much), and turbo lag was increased by a noticeable amount. For me, I wouldnt bother doing it again, I’d just buy a faster car in the first place, less hassle all round.