Notice that every other hole is offset to the left of the center circumference, with alternating holes offset to the right. It’s ABSOLUTELY essential that spokes from the left hand hub flange go to left-offset rim holes, and spokes from the right hub flange go to the right-offset rim holes.
If you were to do it the other way, spokes would cross the center circumference, with each spoke entering the rim at an unacceptably shallow angle rather than the preferable 90 degrees (perpendicular).
The necessity of not crossing the center circumference constrains your wheel building possibilities.
but I read elsewhere that crossing them would build a stronger wheel (but a bit heavier due to longer spokes).