I’ve recently switched from Maxxis to Specialized tyres and actually got round to putting them on yesterday.
In my experience, geting a single ply non UST Minion/High Roller 2.35 onto either a UST rim or a Flow was a massive ballache. The floppy sidewalls made it hard work and I needed a compressor to get them to seat.
I also found I needed a ‘lot’ of sealant to make them work.
By comparison, the 2Bliss Eskars I’ve just put on went up with virtually zero effort on both the above wheelset from a track pump and I used a third of the amount of sealant.
The other advantage seems to be that a comparative sized tyre is about 250g lighter than the Maxxis ones I took off. I have no idea where all the weight is hiding on a single ply Maxxis. If you use skinnier tyres, that may not be so relevant.
Thumbs up from me.