More difficult to set up.
Bad wire routing. Look where the wire ends up!
Poorer shifting.
Noticeable lack of longevity compared to normal mechs. In theory they should be more out of the way and therefore last longer, but in practice they seem to require replacing more often.
Issues when used with SRAM cassettes.
I base that on my own personal use of several XT shadow mechs and years working as a bike mechanic wrestling with the things since they were introduced, trying to make them seem good on bikes we are trying to sell people.
I can’t say that I’ve yet had much dealings with the new 10 speed systems though.
Have I found the first fellow bike mechanic who actually likes them?