Short cage is marginal (it’s too short to work reliably on all bikes even without the OneUp- I have to run an 11-28 on my Orange as the chaingrowth means a Shimano short cage won’t work with 11-32T, it can’t take up the chain slack. nothing to do with the range adjuster before anyone says it!) OneUp don’t recommend any short cage mechs for the 42T.
Medium should be alright on most bikes, worked fine on my hardtail though tbh I do wonder if the longer arm of a long cage might take up the chain better. Would like to try it but don’t have any long clutchy mechs.
Chaingrowth is basically the random factor, some bikes are extremely “stretchy” and if the mech’s already using up all its margin on taking up the extra chain from the 42T, it can’t deal with the chainlength change.