I have exo cased tyres on my Five which is set up as a more sturdy bike (36’s, 1×10, chain guide, wide bars, short stem etc etc) that does a bit of everything, i don’t run the tyres as low as i could with dual ply’s but still low enough to get good grip, i push them quite hard riding techy rocky trails as well as dh at Gawton and they hold up pretty well. I have a 2.5 st minion dhf up front and a 2.4 hr2 60a on the rear. Yes they are a lot lighter and as a consequence aren’t as tough but the trade off is a happy medium for me – don’t go silly on the pressures and you’ll be fine.
As a comparison i’d say they are similar, possibly tougher than continentals protection casing on my Barons.