Thinking about it, I wouldn’t be surprised at all if a third party was selling software purporting to run Trim commands on SD cards, but if so you can almost certainly file these in the same snake-oil BS category as RAM doublers (remember those?) and SSD defragmenters.
As I said before, Trim is a feature on AHCI interfaces (and SAS but let’s ignore that for simplicity). Ie, it needs to be a SATA SSD connected to a SATA interface in AHCI mode. This is the same reason why you can’t Trim an SSD in an external USB caddy – although it’s an SSD, you’re not attached to an AHCI-capable interface, you’re attached to the USB interface, so no Trim.