I’m really into my CdF. I just love the versatility / off road ability with 95% of road bike speed, and it’s just great fun. The only thing is, it’s not a light bike and a lot of that weight is in the frame (and the steel fork in my case although the frameset comes with a carbon fork). With light skinny tyres I’m sure it would be even faster on road but you’d lose a lot of the versatility.
I really like the TRP HyRds on mine, they’re worth considering although they seem quite pricey aftermarket. If I was building from scratch I think I’d want to stretch to Shimano 105 hydros.
Have a read of some of my thoughts (inc brakes) here if you’ve got time.
http://singletrackworld.com/forum/topic/new-bike-genesis-cdf