worst i have seen is alloy nipples corroding but this is white powder (presume aluminum oxide?) not red rust, which must be from steel eyelets rather than brass/alloy nipples or rim. Not all rims created/finished equally though: seen loads of paint lift off brown ones as featured on “That Crap Run Of DT Wheels That Kept Breaking On Specialized Circa 2008”, whereas we have some many years/rides old black ones with and without eyelets that are still lovely.
Also +1 to lubing nipples when you build, but this is for building/holding off spoke twist/deflection, and not protection against corrosion. (Wheelpro book sayeth so, and this has done me very well over 25 or so of mine and mates’ wheels) Also top tip for less spoke deflection (and that awful feeling when you stress the wheel sideways on the floor and all the twisted spokes ping their way back out of tension), once your wheel is laced up and not loose-but-not-tight, get a bit of lube in where each spoke crosses and rubs against the other too (but clean it all off with a paper towel when you are sure you have finished tensioning.)
As a rule lube/oil is not good for tyres or tubes, not sure how happy I would be deliberately and regularly applying it so near by, especially with cloth rim tape and tubes.