I think you have to look at the area to decide. A wildlife trust reserve with specific ‘no bikes’ signs is a different situation to using a public footpath that is rideable.
One is using an existing right of way but with the wrong transport, the other is permissive access to begin with usually. I would probably say you shouldn’t ride it. The wildlife trusts are often doing conservation work, and there may be good reason for no bikes.
However, as mentioned above – if it is marked as open access land on the OS maps, then i would perhaps think differently about it. There is access for anyone on foot so why not on your bike?