Thinking about danger – riding a bike on the road exposes you to a (small) risk of injury or death.
In the 2016 edition the riders in the TCR racked up 655,080 km. If you have an event where people are covering that sort of distance, even for a relatively low-risk activity like riding a bike on the road you will inevitably have some accidents.
In an event such as the TCR the risk profile will not be exactly the same as normal road riding.
In the TCR you’re more likely to end up riding on deserted roads in the middle of the night (possibly safer than daytime providing you’re well lit up?). You may choose to ride on straight, fast roads which get you to your destination more quickly rather than the small back roads you might otherwise take (more dangerous?). You will probably end up tired and riding when not as alert as you might like to be (more dangerous).
It’s absolutely tragic what happened to Frank, but I don’t think we should abandon ultra racing because of this incident.