Not convinced about the saddles with central cut-aways, as a bloke I tried and binned one for the same pinching reasons as mrsholly 😳
mrsT has a Myka for gentle trail riding, she has arthritis, and is OK with the standard seat atm.
mrsholly sounds like she is a tall lady or is the bike just too big?
shorter stem, straight seat post and saddle further forward, tried that yet? Assume shorts have good padding, in the right area and it is not these that are causing the irritation?