I’ve had a handful of similar frames, including a Cotic X, Escapade, Surly Ogre, Kinesis 4S and Surly Straggler in recent years.
The bikes that the OP would naturally consider will all be slightly different and it will depend on what emphasis you place on different needs.
I ran the Escapade with 28-37c tyres and various setups, including flat bars, singlespeed and a good few others. It’s a fairly light frame for what it is and has a decent number of mounts, but with a tall front end it’s definitely not a classic road racer. I used it for commuting, touring and the odd sportive – it was most comfortable with its use in that order.
After going back to a single bike for all my road needs, I’ve ended-up with a Straggler. The frame is notionally the heaviest, but it’s really very good quality and I’m impressed with the mounts – they just work better than any other frame I’ve put pannier, mudguards and cages on. It has clearance for 50c tyres / mudguards, which I currently run with either 41c Knards on Hope 20Five wheels or 28c GP4S tyres on lighter Kinesis Racelight wheels.
Overall, I’d say that the Surly is the most versatile and has the more classic geometry for road riding – whereas the Escapade is slightly better suited to comfortable and “safer” riding, and isn’t quite as versatile.
Others to consider would include the Genesis range.