I have experienced unaccountable chainsuck on a small 456 frame I built up for a girlfriend. Brant, who has never met her, leave alone watched her riding, says that this is down to poor shifting on her part. Suffice to say she never experienced any such problem on the many other bikes she has owned. The other slight problem with Brant's view is that many other people have described the exact same problem with these frames in posts on here.
I have the Ti456 and a Steel one, both 18". I have enjoyed them both very much and they are very capable bikes which have given me very few problems. The Ti456 was not comfortable with external bb's but now I've reverted to square taper and an old Middleburn crank it is quite happy.
I personally think there is a sizing issue if you are around 6' tall. The 16" is too small and the 18" is too big, but that may have something to do with my expectations and the way I ride as opposed to what Brant does.
The medium Pace 303 seems to be more my sort of fit and lends me far more confidence in the descents and twisty bits. The On One probably performs better at everything else.
Finish quality was better on the three On One frames I've built up than it was on the Pace frame.