Spent my first 25 odd years in Wycombe. Not the best place in the world nor the worst place.
Avoid Castlefield, and Micklefield, unless you want your bike stolen on a regular basis. Desborough area is full of students, which you may or may not like. The sands area, to the west of Wycombe, by the football ground is ok. Some of the ‘villages’ which I grew up in, like hazlemere, holmer green are ok if very twee and middle class.
Depends how far out you want to live really. If it was my money, which it was, I’d rent in Downley, which I did. Not too far out of town but not to close either. Also close to west wycombe and the chilterns for some good riding. Dunno if it is still let by the same guy, but ace landlord, let me know if you want his number. I may have it somewhere.
If you have any specific areas/questions give me a shout. Like most places you can have good areas that are only 5/10 minutes drive away from crap areas.