The ISIS system is rubbish for two reasons:
1) Bearing balls are far too small, so BB’s fail prematurely.
2) There’s no proper wedging action in the crank to axle inetrface, so perfect machining of the crank and axle are vital. Manufacturers do not usually make anything 100% perfect. If the crank bore has machined undersize and the BB oversize, then you’ll get a nice tight fit and it’ll be fine. If it happes to be the other way then one or other of the cranks will loosen on a ride. Once ridden loose the bores open up and they’re scrap.
I’ve had loads of trouble with ISIS, and am going back to good old square taper. I’ve knackered FSA, Truvative, FRM. Of all the BB units I’ve been used, only SKF seems to last. My SKF 600 has expensive CNC machined FRM crank arms fitted, which have been affixed with epoxy resin since new to stop them creaking.
ISIS is rubbish!