It's a very good question. On the Enduro it will be dead easy; the adjusting taps are set at the head of the resevior at 45 degrees so they will be very easy to access. Failing that, the damper comes with a very natty adjusting spanner that allows to access the taps wherever they are. On the Demo 8 for example is pretty tricky.
Also have a look on MTBR.com forums as there were always discussions of this sort on there and a large number of people ended up running the CCDB on their 05-07 Enduros.
I would have put one on mine but I ended up breaking the frame terminally so I ended up putting one on its Nicolai Helius AM replacement.
Other tips; don't bother ordering it with a ti spring as Cane Creek only supply 3" and 3.5" stroke Ti springs. They work fine but you end up carrying far more material than you need and thereby negating the weight advantage.
If you're going to order one, Freeborn are doing a good deal on them at the moment: £481.
The thing I like most about what it does is the separation between the low and high speed. On other dampers you end up in a compromise between the low speed damping and sensitivity over smaller (but still high speed) inputs. For example, with Pro-Pedal, when you have it set to medium or higher levels, it inhibits the initial part of the shock movement so although you get a firm feel to bike, you get poor grip of smaller roots and rocks. With the CCDB, you can dial in a decent amount of low speed compression so that you can really pump and accelerate the bike over rolling terrain, but even over the smallest of ripples the thing opens up and you get oodles of grip.