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My wife (same age as me, 53) had AZ yesterday morning. Absolutely floored the poor lass! Cold, then hot, then achy and just feels terrible. Not sure she slept at all last night. I had Pfizer 3 weeks ago and had nothing more than a sore arm.
I'm sure it'll get me second time round tho.
Had mine yesterday at 2pm (50) AZ, felt ok until about 11pm and started to get the shivers really bad, didn't sleep much, just generally feel groggy like having a heavy cold and arm aches a bit.
The greater your immune response to the vaccine ie : feeling flu’y, aches pains etc the better as it means your body has developed a strong antibody response to the vaccine, I’d be more concerned about having zero immune response to the vaccine ie : you felt pretty much normal with no ill effects.
Peer reviewed evidence to back that up?
I’ve had at least 6 different types of vaccine shots over the years (probably more) & I’ve a. never heard that before & b. never developed any side effects from any except Yellow Fever. No Rabies, no Hep, no Meningitis, no TB. NONE.
(Bar a few hrs feeling a bit bleurgh from Yellow Fever as already mentioned.)
57 in a few weeks. AZ a fairly bad headache for 2 day after the jab, but that was it. Mrs Bloke, 55 AZ, laid flat with flu like symptoms for 24 hours. Didn't get out of bed.
The greater your immune response to the vaccine ie : feeling flu’y, aches pains etc the better as it means your body has developed a strong antibody response to the vaccine, I’d be more concerned about having zero immune response to te vaccine ie : you felt pretty much normal with no ill effects.
I thought that, but it appears it's not true. Link:
https://www.bbc.co.uk/news/health-56375307
From that link: "Selfishly, I had hoped that having side effects meant I had an incredibly strong immune response and there has been some evidence from previous vaccines that this would be the case.
"There are examples, like pandemic flu in 2009, where stronger side effects meant a strong immune response," said Prof Pollard.
But that is not the case with the Covid vaccine, everyone is getting roughly the same protection.”
On the protection / side effects thing, this is from the BBC article already linked several times. In short, you only need a small initial response to generate the adaptive response that's needed to provide virus-specific, longer term protection. Good article and the BBC Sounds podcast linked to it is worth a listen if you're interested:
> https://www.bbc.co.uk/news/health-56375307 <
Selfishly, I had hoped that having side effects meant I had an incredibly strong immune response and there has been some evidence from previous vaccines that this would be the case.
"There are examples, like pandemic flu in 2009, where stronger side effects meant a strong immune response," said Prof Pollard.
But that is not the case with the Covid vaccine, everyone is getting roughly the same protection.
"It's fascinating, even though the elderly had few side effects, they had exactly the same immune response."
The explanation comes from how the two halves of the immune system work together.
The first is called the innate response and includes that chemical fire alarm. The other half is the adaptive response which learns and then remembers how to fight an infection by designing B-cells that produce antibodies to seek out and destroy the virus, as well as T-cells which can attack any of the body's cells which have been infected.
Prof Riley said: "It's this early innate phase of the immune response that varies with age and varies amongst people and that's what determines the strength of your side effects.
"You only need a little bit of that innate response to wake up the adaptive response and get that full panoply of B-cells and T-cells that will protect you."
I thought that, but it appears it’s not true. Link:
Good link, thanks 👍.
Like I said: at least half a dozen different vaccine jabs over the years & only ever had one slight reaction (Yellow Fever).
59 AZ vacine 2pm yesterday.
Feels like a very minor bruise where I was injected.
59 here. AZ on Thursday afternoon, fine until I went to bed, then a spell of hot, sweating, fast heart rate at about 3 am, woke with hangover symptoms, had 2 paracetamol before breakfast and was right as rain by lunchtime. Reading the leaflet, I had a Full House of the Very Common side effects but nothing else, and all over within 24 hours.
Since I know too many people who've had Covid and its after-effects, that's a very good deal as far as I am concerned
Mrs Inbred works for NHS and has had both jabs both Pfizer, no reaction after the first other than a slight dead arm. Second jab floored her. Extreme fatigue and tiredness, aching joints etc for 2-3days. I’ve had the first AZ jab, symptoms were mild common cold like and aching joints for 2-3 days. 2nd jab due in May we’ll see how that goes.
Is there any link between the severity of the side effects and a previous Covid-19 infection?
From the BBC article linked above, about five times now 🙂
'Another factor that slightly increases the chance of side effects is having had a previous coronavirus infection, which can lead to an incredibly strong immune response after vaccination.'
I'm sorry, I didn't realise it was necessary to read every single linked article in the thread before asking a question.
I’m sorry, I didn’t realise it was necessary to read every single linked article in the thread before asking a question.
I mentioned it in case you were interested and because it's a good article. The only reason I said it had been linked five times was because doing it again felt like overkill. Also there was a smiley which is supposed to stop people posting pissy comments instead of just, you know, saying something along the lines of: 'Thanks for answering my question' 😉
I wasn't trying to say you should have read the article.
Thanks for answering my question 🙂
Me and the Mrs both had our first AZ Wednesday afternoon.
Me, I woke next day with an achy arm and by mid day felt quite nauseous until Friday tea time. In fact I nearly cancelled Saturdays ride as I still felt like I had an hangover.
Mrs, she was proper poorly next day. Cold sweats, headache and feeling nauseous. She was fine by Friday.
You're welcome 🙂
I'm 50 and had the AZ one yesterday morning. Sore arm today and maybe feeling a bit more tired than I'd like, but it's hard to say if that's more the effect of the vaccine or a busy week. All in all nothing to write home about.
Peer reviewed evidence to back that up?
I apologise, I did not realise we are now running a peer reviewed forum
My consultant mentioned that a number of patients under his care (ie - with active ms and other immune system driven illnesses) developed an increased response to the vaccine which has totally floored them and been found to have an increased antibody response to a single covid vaccine over the general population, studies are ongoing and ive allowed him to include my situation in with them.
I interpreted that to mean what I wrote above regarding immune response, probably shouldnt have as I am not a doctor/scientist etc.
Had mine at 1100 yesterday morning.
Felt OK, slept OK.
Woke up with a sore arm this morning and started feeling pretty crappy this afternoon. Slight headache and sore muscles. Just took a couple of paracetamol.
Update: Had mine Friday am. Slight underlying headache lasted 30 hrs or so. Arm is slightly sore to touch. Other than that, nothing. Just back from a hilly 62km gravel ride and feeling great.
Had mine Sat evening...52 yrs. Felt good after, and snaffled a nice Thai takeaway for tea. Fell asleep during ep 2 of the Flight Attendant (normal for me). Slept OK. Up early to let dog out, then lovely woodland walk in the sun, mentally planning a nice gravel ride....then it hit hard when I got home! Shivers, aches,really tired. Set up my new hooped bivy in garden, but even that knackered me out so snoozed for a couple of hours (in the bivy!). Damn it if it wasnt the best weather day of the year so far....gutted. Still, now had the jab, but the day after didnt exactly go as planned 🥵
41, previous COVID sufferer.
Had most of the obvious stuff - light headedness, dizziness, aching joints, fatigue, hot and cold shivers, sleepless night, general roughness. Then, about 48 hours in, I had my first ever migraine, which was interesting if not particularly fun.
Now about 72 hours in, I feel broadly achey like I spent yesterday digging the garden, and the jab site is still pretty bruised, but otherwise not too bad.
Nothing so far. But it was only 15 mins ago. Pah, letdown!
8 hours post AZ - nothing do far for either of us so far - but I guess any side effects will be overnight
Had the AZ jab this morning at 10. Had been feeling a bit coldy yesterday eve (kids back in nursery, snotty noses, tested, not COVID). Still feel a bit coldy. Slightly bruised feeling on arm and perhaps bit of a headache perhaps but nothing else yet! See what happens tomorrow.
@somafnkndid your consultant say anything about their ms after vaccination? If taking B cell therapy, vaccines are recommended prior to initiation, as your about to nuke your B cells that produce antibody.
I find that immune responses set off my auto immunity, nothing as severe as MS, but I get psoriasis flares and aching joints.
I’m not on anything for my spms apart from sativex for muscle tone, tried to get siponimod last year but it’s not been appraised for use yet and as such there’s no timeframe for release. Hope they get their finger out soon as my lower half is practically useless and my upper half is catching up with it rapidly, can stand up if I pull myself up and lock my knees as far back as I can but need to throw legs from hips to shuffle about house whilst holding on to stuff with both hands. Thankfully I’m slowly recovering from vaccine response but I was as good as a corpse for near enough a week, could barely turn over whilst in bed due to tone and deep aches/pains in every joint. Got movement back in right ankle and very slight movement over right leg but left leg control is gone for good.
Psoriasis is a helluva condition, my mate suffers badly from flare ups all over his body and I see him attempting to act as normal as possible but I know when he’s really suffering, it’s a complete shit that our own immune systems have turned against us eh.
Had mine at 3pm yesterday. Fever of 39.5 within 12 hours and a pretty unpleasant night with non-stop shivering. Temp down to 38.5 with paracetamol. Not particularly looking forward to the next one in 12 weeks.
Had mine at 3pm yesterday. Fever of 39.5 within 12 hours and a pretty unpleasant night with non-stop shivering. Temp down to 38.5 with paracetamol
Exactly the same for me, but I had mine at 12:30 yesterday.
I was feeling pretty good going to bed, then BAM 3am I’m woken shivering like mad because my shoulder is out of the duvet. Mental.
I’ve not felt like this in the morning since that night on the Mitsubishis in 1999!
Still, it’s not nearly as bad as the time I had flu, and I’m already starting to feel better. Not slept since 3am though.
Not particularly looking forward to the next one in 12 weeks.
Based on nothing but my wife’s experience and her colleagues, those who had a rough ride the first time didn’t the second and those who had a easy ride the first time had it rough the second.
Had mine on Saturday afternoon (Oxford one).
Fine for Saturday evening but got aches across my upper arms, shoulders and upper back yesterday and felt pretty drained yesterday evening.
Woke up this morning and feel fine now.
Get it done! 🙂
morning update, 14 hours on. A disturbed night, too hot and then too cold but not exactly shivering or burning up (predosed paracetamol as precaution, maybe that had effect?)
This am - splitting headache, like a real Withnail '****er behind the eyes' more paracetamol at 6am, easing now. But like muffin man, aches from middle of back upwards, across shoulders and neck and in all my joints. All of them, even my fingers / knuckles feel achey.
I feel I've maybe got the milder end of it....but maybe it's all about to kick off big style. We'll see.
Got AZ on Saturday afternoon. It hit me like a ton of bricks around 2am. Headaches, chills, nausea, the works. Spent all day in bed yesterday and still feel ropey this morning.
Really hoping the anecdotal "second one isn't so bad" turns out to be true.
Oh and I'm 46, if that counts for anything.
Got the OxAZ late Sunday afternoon.
Got a good nights sleep. But woke feeling tired. Upper left arm pretty achy; rest of body starting also to feel tired (as if done a big ride yesterday). Am feeling slightly spaced out/that jet lag feeling.
50yrs of age.
Stiff leg and an itchy ear.
Not actually had it yet, but reading through some of the replies, it could be said how many are the result of something else and could get mixed in to how you are feeling, given you are expecting results of some sort. Might even be some sort of placebo effect going on too.
So don't worry yourselves into an early grave 😆
I'm 48 hrs in from the AZ vaccine and I feel fine. Decent night's sleep, arm was slept on so so issues with the shoulder, no nightmares which was a shame 😭😂. Been out on the bike this morning.
I wonder if my daily (over) dose of vit D for the past 3 months had helped? By over I mean will within tolerable levels around 1000iu/day.
My right index finger turned into a USB plug and my consciousness was uploaded to the Internet leaving my physical shell behind
Update on mine - I had it on Friday at 5pm. Felt out of sorts all day on Saturday - no specific 'thing' to pinpoint, just a general feeling of lethargy and not being quite right. Woke up yesterday morning feeling much better (pretty much back to normal) however my arm still hurts now.
Exactly 3 weeks to the day of having mine and this morning was the first time I've woken feeling vaguely normal, might actually be able to do something productive for a change. Will pop into town later to lick some door handles, put this thing through its paces.
46, got it early Sunday evening.
decent nights sleep. arm doesn't hurt. maybe a little dizziness, but it's difficult to tell as the trees are budding and my sinuses are going mental anyway!
will see how this goes.
what was quite something was having it at the Louisa Jordan. I know the SEC from gigs and events. to see it as a pop up hospital felt like you're wandering through a movie set. It's quite scary to think of what could have been and relating it to what has and is continuing to be (i.e. 125k+ deaths).
Wife (40) had the AZ jab yesterday morning. The chills hit around 4pm, fever of 40 degrees by 8pm! Couple of paracetamol eased it a little. Sweats all night, feels like shes been hit by a train this morning. Temp is down a bit (38.5-39) so hopefully on the mend.
Exactly the same for me, but I had mine at 12:30 yesterday.
I was feeling pretty good going to bed, then BAM 3am I’m woken shivering like mad because my shoulder is out of the duvet. Mental.
I’ve not felt like this in the morning since that night on the Mitsubishis in 1999!
Still, it’s not nearly as bad as the time I had flu, and I’m already starting to feel better. Not slept since 3am though.
After feeling like death since 3am I’m starting to come out of it. Lifting as quickly as it came.
My advice to anyone is to predose normal run of the mill paracetamol the first night after your jab and keep taking them 2 every 4 hours up to 4 times a day for a day or two and you’ll be reet.
Update.
Spent the afternoon asleep. Totally knackered, bit of a headache, but nothing too bad but kinda dizzy with it.
Seems to be easing now though
another 12 hours on, 24 since jab - a bit warm but not burning up, headache mainly gone, joint pain has not. Most notable in hips and fingers, still have this muscular ache across the upper back. Arm now sore too. Mild nausea every now and then.
In myself though, not exactly ill, but have slept off and on most of the day, and I'm never one for lazing around in bed. So I must be REALLY ill......wife is unconvinced.
As an aside, first day off sick in about 15 years. I was that git that always turned in while sneezing and coughing everywhere. I absolutely will not be doing that when we're back to normal, I think we're all more 'hygienic' now aren't we?
Will pop into town later to lick some door handles, put this thing through its paces
🙂 🙂
I'll be doing the same thing when I get mine 🙂