Doubtful
Nobody makes an off the shelf 10spd mech that works well with a 42T big cog yet. You can get OK shifting across the block with an 11-40, but not an 11-42 without a Rad Cage or Goat link or the like. 11spd mechs have been designed ground up, to work with wider ranges.
Also… Ratio jumps of more than 20% are quite noticable, and annoying in use. Anything of 20% or under seems to be acceptable, but above that and it’s less than ideal. For instance, I’ve been running an E13 9-44 11spd cassette for a while now, and it’s superb, but I do really notice the jump from the 14-17 cogs, a 21.5% jump (the biggest % jump in the block) which is quite annoying. The rest of the jumps (all below 20%) are perfectly fine.