have some computing power to do analytics on the database and run simulations
If you’re even looking at Xeons and care about performance, go for the xeons.
AMD aren’t competitive just now on performance, though maybe are on cost in the mid/low range. Still, nearly everyone uses intel.
What sort of simulations, what sort of analytics? If you know this, surely you can answer the questions as to what sort of machine you need. If you don’t, ask whoever’s writing the sims/analysis code?
I do a lot of fairly high end computing, and the only thing that’d tempt me off Intel is power8 and I don’t have the budget for that…. that NVlink IO though…
(caveat to all the above, I do a lot of high end compute but DBs aren’t my thing at all)