Anthony Hopkins as Hannibal Lektor in Silence of the Lambs

Jack Nicholson in One Flew over the Cuckoo's Nest

Louise Fletcher as Nurse Ratched in the same film as she made you want to hate her.

Robert Downey Jr in just about anything- possibly the finest actor of his generation

Kathy Bates- Misery.

Debbie in Debbie does Dallas

Haven't read the rest but the two stand out ones recently for me were:

Daniel Day Lewis in There Will Be Blood and Michael Fassbender as Bobby Sands in Hunger.

Robert Depardieu in Danton, good in Cyrano too, although the death scene is a bit OTT.

Richard E Grant again BUT how about in 'How to get ahead in advertising' (although Withnail is to drawer to)

Hopkins in The Bounty – http://www.youtube.com/watch?v=wUlgVqSeLRk

Not to be negative but Heath in the dark knight was pants – and to edit the whole film around his none perforamce made for a shocking follow up to Batman begins.

Christian Bale is a great actor – keep the batman franchise with him and we will be much better off/

Yes, I know you will all disagree, but it is in fact all about me

Nah, Gary Oldman is the great actor in the Batman series.

Jack Nicholson – A Few Good Men

Daniel Day Lewis. Gangs of New York, Last of the Mohicans.
Robert Carlisle. Ravenous.
Charles Durning. Choirboys. Tootsie.
John Cusack. All of his films.

John Turturro-Jesus Quintana- Big Lebowski

In fact any of the main cast in that, Bridges, Buscemi and Goodman

deluded – Member
Sir Ben Kingsley as Don Logan in Sexy Beast – terrifying

When asked how he prepared for the part, Sir Kingsley said he didn't have time, so he just thought of his Grandmother… 😯

Meryl Streep in "The Devil Wears Prada".

The "Why you are wearing that jumper" speech to "Emily" is, I would argue, her finest moment.

Matt Damon

Michael Fassbender as Bobby Sands in Hunger

Amazed it took us to page 4 to get this.

the most haunting film performance I have seen for some time – indeed, the whole film is simply extraordinary.

The "Why you are wearing that jumper" speech to "Emily" is, I would argue, her finest moment.

I have heard she's in line to play the Sainted Margaret in a biopic of the former She Who Must Be Obeyed.

So that should read "her finest moment so far", probably.