I've just started doing a bit of this, and it seems to me that the best way to plot the course is probably on the satellite image, using the OS map window as a 'mapping' reference only.
I think that thsi should give a better 'on the ground' fix, as the OS maps are intentionally distorted to enable good portrayal of features such as tracks and buildings etc. So I use the map to check the route, and plot the GPS stuff based on the satellite image which clearly (in most cases) shows the actual path / track / feature that I'm heading for next.
I've also noticed that, with the Etrex Vista HCx the map page is in essence so small as to be difficult to read when riding. The recommendation in mbr recently was to use the 'Highway' page, which has a more schematic style of representation of the track immediately ahead, much like the SatNav stuff that most of us use in cars on occasions.
The 'course bearing' pointer (compass page) seems too sensitive, and tends to point you into ditches or shrubs when in close proximity to a 'waypoint', so I guess that the 'Highway page' is the best solution in that respect.
Any advice from other users of similar products appreciated.