I run a Chilli one on the front. It is the same width knob-knob as the 2.2 RQ on the rear but the casing is narrower but still quite tall. Definitely bigger than a 2.35 minion but narrower than a 2.5 HR. They have quite a round profile on my DT Swiss 5.1d rim (28mm wide) compared to a 2.2 RQ on the same rim.
I have found that it needs something to bite on, probably because the knobbles are rather big. On smooth hardpack it feels a bit squirrely and vague through corners but on soft ground or loose stuff it is great. Very consitent bite at all angles of lean so far and works very well under braking. Really liking it for natural stuff but I imagine trail centres would be better suited to a less knobbly tyre.
Side walls seem tougher (Apex reinforcement or something I think?) than the rubber queen but I've not had any trouble with either in the UK. They seem to resist pinch flats well (based on me riding down steps with pressure somewhere around 15psi. I could see them deforming almost to the rim and I was waiting for the bang and crash...but it never came.) Certainly tougher than ADvantage or Crossmark sidewalls!
I personally wouldn't buy non-chilli contis for wet or slippy riding. And although they are pricey the chilli compound wears very well.