As long as you stick with a hand biuld you can’t really go wrong, if you run shimano the 105 open pro combo seems prefect, I’ve had centuar hubs with opens pro rims for years and years and they weren’t new when I bought them, mine are heavy but in winter I’d trade realibility for weight and speed anyday, especially if you like me you ride at night on unlit roads.
I’d just steer clear of factory built wheels as if you ding a rim they can be hard to find straight away and can be a fortune to replace.
A lot of the lads I ride with seem to like ambrosio hubs with open pro rims, I think they’re be my next wheels for my winter bike